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Literature DB >> 6429221

The haemodynamic responses to incremental doses of intravenous nitroglycerin in left ventricular failure.

Abstract

The effects of incremental dose infusions of nitroglycerin, 10-160 micrograms/min, on pulmonary capillary wedge pressure and other haemodynamic variables have been studied in patients with left ventricular failure. Intravenous (IV) nitroglycerin caused a dose-related improvement in myocardial performance, with significant reductions in the raised pulmonary capillary wedge pressure and systemic vascular resistance. At the lowest dose of infusion only the venodilator action of nitroglycerin was apparent. From 40-160 micrograms/min the associated arteriolar dilatation was associated with a consistent improvement in myocardial performance.

Entities: Chemical Disease Species

Mesh：

Substances：
Nitroglycerin

Year: 1984 PMID： 6429221 DOI： 10.1007/bf00265803

Source DB: PubMed Journal: Intensive Care Med ISSN： 0342-4642 Impact factor: 17.440

16 in total

1. Variant angina pectoris. Clinical presentations, coronary angiographic patterns, and the results of medical and surgical management in 42 consecutive patients.

Authors: A D Johnson; H A Stroud; W V Vieweg; J Ross
Journal: Chest Date: 1978-06 Impact factor: 9.410

2. Effect of sublingual nitroglycerin in emergency treatment of severe pulmonary edema.

Authors: W D Bussmann; D Schupp
Journal: Am J Cardiol Date: 1978-05-01 Impact factor: 2.778

3. Measurement of cardiac output by thermal dilution in man.

Authors: M A Branthwaite; R D Bradley
Journal: J Appl Physiol Date: 1968-03 Impact factor: 3.531

Review 4. Intravenous nitroglycerin. A review of pharmacology, indications, therapeutic effects and complications.

Authors: N S Hill; E M Antman; L H Green; J S Alpert
Journal: Chest Date: 1981-01 Impact factor: 9.410

5. Beneficial effects of intravenous glyceryl trinitrate in a case of Prinzmetal angina.

Authors: E Antman; S Gunther; W Barry
Journal: Br Heart J Date: 1980-01

6. Nitroglycerin as a hypotensive drug during general anesthesia.

Authors: N R Fahmy
Journal: Anesthesiology Date: 1978-07 Impact factor: 7.892

7. Effects of intravenous nitroglycerin on left ventricular function and ST segment changes in acute myocardial infarction.

Authors: J T Flaherty; P C Come; M G Baird; J Rouleau; D R Taylor; M L Weisteldt; H L Greene; L C Becker; B Pitt
Journal: Br Heart J Date: 1976-06

8. Reversal by phenylephrine of the beneficial effects of intravenous nitroglycerin in patients with acute myocardial infarction.

Authors: P C Come; J T Flaherty; M G Baird; J R Rouleau; M L Weisfeldt; H L Greene; L Becker; B Pitt
Journal: N Engl J Med Date: 1975-11-13 Impact factor: 91.245

2. A possible explanation for the absence of anti-anginal properties of transdermal nitroglycerin units: an echocardiographic study.

Authors: E D Bennett; A L Davis
Journal: Br J Clin Pharmacol Date: 1985-04 Impact factor: 4.335

The haemodynamic responses to incremental doses of intravenous nitroglycerin in left ventricular failure.

1. Variant angina pectoris. Clinical presentations, coronary angiographic patterns, and the results of medical and surgical management in 42 consecutive patients.

2. Effect of sublingual nitroglycerin in emergency treatment of severe pulmonary edema.

3. Measurement of cardiac output by thermal dilution in man.

Review 4. Intravenous nitroglycerin. A review of pharmacology, indications, therapeutic effects and complications.

5. Beneficial effects of intravenous glyceryl trinitrate in a case of Prinzmetal angina.

6. Nitroglycerin as a hypotensive drug during general anesthesia.

7. Effects of intravenous nitroglycerin on left ventricular function and ST segment changes in acute myocardial infarction.

8. Reversal by phenylephrine of the beneficial effects of intravenous nitroglycerin in patients with acute myocardial infarction.

9. Intravenous nitroglycerin in acute myocardial infarction.

10. Combined hemodynamic effects of dobutamine and IV nitroglycerin in congestive heart failure.

1. Acute Heart Failure Treatment.

2. A possible explanation for the absence of anti-anginal properties of transdermal nitroglycerin units: an echocardiographic study.

3. Lack of tolerance in forearm blood vessels in man to glyceryl trinitrate.

Review 4. Nitrates in congestive heart failure.

5. High dose nitroglycerin treatment in a patient with cardiac arrest: a case report.

6. New perspectives of nitric oxide donors in cardiac arrest and cardiopulmonary resuscitation treatment.