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Literature DB >> 6429

Glutamate dehydrogenase: genetic mapping and isolation of regulatory mutants of Klebsiella aerogenes.

Abstract

The gene for glutamate dehydrogenase (gdhD) has been mapped in Klebsiella aerogenes by P1 transduction. It is linked to pyrF and trp with the order pyrF-trp-gdh. Complementation analysis using F' episomes from Escherichia coli suggests an analogous location in E. coli. Two mutants able to produce glutamate dehydrogenase in the presence of high levels of glutamine synthetase have been isolated. One, tightly linked to gdhD, shows normal repression control by glutamine synthetase but produces four times as much glutamate dehydrogenase activity as does the wild type under all conditions tested. The other revertant is not linked to gdhD or glnA.

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Year: 1976 PMID： 6429 PMCID： PMC233044 DOI： 10.1128/jb.127.1.141-148.1976

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

18 in total

1. Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase.

Authors: F Foor; K A Janssen; B Magasanik
Journal: Proc Natl Acad Sci U S A Date: 1975-12 Impact factor: 11.205

2. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

3. Identification of the structural gene for glutamine synthetase in Klebsiella aerogenes.

Authors: A B Deleo; B Magasanik
Journal: J Bacteriol Date: 1975-01 Impact factor: 3.490

4. Role of amino acids in osmoregulation of non-halophilic bacteria.

Authors: J C Measures
Journal: Nature Date: 1975-10-02 Impact factor: 49.962

5. Transduction of chromosomal genes between enteric bacteria by bacteriophage P1.

Authors: B M Tyler; R B Goldberg
Journal: J Bacteriol Date: 1976-03 Impact factor: 3.490

6. Glutamine synthetase and the regulation of histidase formation in Klebsiella aerogenes.

Authors: M J Prival; J E Brenchley; B Magasanik
Journal: J Biol Chem Date: 1973-06-25 Impact factor: 5.157

7. Activation of transcription of hut DNA by glutamine synthetase.

Authors: B Tyler; A B Deleo; B Magasanik
Journal: Proc Natl Acad Sci U S A Date: 1974-01 Impact factor: 11.205

8. Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes.

Authors: J E Brenchley; M J Prival; B Magasanik
Journal: J Biol Chem Date: 1973-09-10 Impact factor: 5.157

9. Genetic control of glutamine synthetase in Klebiella aerogenes.

Authors: S L Streicher; R A Bender; B Magasanik
Journal: J Bacteriol Date: 1975-01 Impact factor: 3.490

10. Gene order of the histidine utilization (hut) operons in Klebsiella aerogenes.

Authors: R B Goldberg; B Magasanik
Journal: J Bacteriol Date: 1975-06 Impact factor: 3.490

23 in total

1. Growth inhibition caused by overexpression of the structural gene for glutamate dehydrogenase (gdhA) from Klebsiella aerogenes.

Authors: B K Janes; P J Pomposiello; A Perez-Matos; D J Najarian; T J Goss; R A Bender
Journal: J Bacteriol Date: 2001-04 Impact factor: 3.490

Glutamate dehydrogenase: genetic mapping and isolation of regulatory mutants of Klebsiella aerogenes.

1. Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase.

2. Protein measurement with the Folin phenol reagent.

3. Identification of the structural gene for glutamine synthetase in Klebsiella aerogenes.

4. Role of amino acids in osmoregulation of non-halophilic bacteria.

5. Transduction of chromosomal genes between enteric bacteria by bacteriophage P1.

6. Glutamine synthetase and the regulation of histidase formation in Klebsiella aerogenes.

7. Activation of transcription of hut DNA by glutamine synthetase.

8. Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes.

9. Genetic control of glutamine synthetase in Klebiella aerogenes.

10. Gene order of the histidine utilization (hut) operons in Klebsiella aerogenes.

1. Growth inhibition caused by overexpression of the structural gene for glutamate dehydrogenase (gdhA) from Klebsiella aerogenes.

2. The glutamate dehydrogenase structural gene of Escherichia coli.

3. The gdhA gene is located at 38.6 minutes on the Escherichia coli map.

4. Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase.

5. gltB gene and regulation of nitrogen metabolism by glutamine synthetase in Escherichia coli.

6. Regulatory mutations in the Klebsiella aerogenes structural gene for glutamine synthetase.

Review 7. The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli.

8. Regulation of glutamate dehydrogenase in Bacillus subtilis.

9. Isolation and properties of Escherichia coli K-12 mutants impaired in the utilization of gamma-aminobutyrate.

10. Salmonella typhimurium mutants with altered glutamate dehydrogenase and glutamate synthase activities.