Literature DB >> 6428401

Inactivation of glucosamine-6-phosphate synthetase from Salmonella typhimurium LT 2 SL 1027 by N beta-fumarylcarboxyamido-L-2,3-diamino-propionic acid.

H Chmara, R Andruszkiewicz, E Borowski.   

Abstract

N beta- fumarylcarboxyamido -L-2,3-diaminopropionic acid ( FCDP ), a novel glutamine analog, inhibits the reaction of glucosamine-6-phosphate synthetase (EC 5.3.1.19) from Salmonella typhimurium LT 2 by irreversible inactivation of the enzyme. The kinetic data on enzyme inhibition and inactivation are presented. It is suggested that the enzyme inactivation occurs according to a sequential mechanism.

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Year:  1984        PMID： 6428401     DOI： 10.1016/s0006-291x(84)80187-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2,4-thiazolidinediones.

Authors:  Radhe Shyam Bahare; Swastika Ganguly; Kiattawee Choowongkomon; Supaporn Seetaha
Journal:  Daru       Date:  2015-01-24       Impact factor: 3.117

2.  Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach.

Authors:  Mohd Shahnawaz Khan; Ranu Agrawal; Mohammad Ubaidullah; Md Imtaiyaz Hassan; Nazia Tarannum
Journal:  Heliyon       Date:  2019-10-18

3.  Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics - synthesis and properties.

Authors:  Joanna Stefaniak; Michał G Nowak; Marek Wojciechowski; Sławomir Milewski; Andrzej S Skwarecki
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

4.  Dapdiamides, tripeptide antibiotics formed by unconventional amide ligases.

Authors:  Jessica Dawlaty; Xiaorong Zhang; Michael A Fischbach; Jon Clardy
Journal:  J Nat Prod       Date:  2010-03-26       Impact factor: 4.050

5.  Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether.

Authors:  Mohamed Reda Aouad; Mariem Mohammed Mayaba; Arshi Naqvi; Sanaa K Bardaweel; Fawzia Faleh Al-Blewi; Mouslim Messali; Nadjet Rezki
Journal:  Chem Cent J       Date:  2017-11-21       Impact factor: 4.215

6.  Synthesis, Molecular Docking and in Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridine⁻Pyrazole Hybrid Derivatives.

Authors:  Eman M Flefel; Walaa I El-Sofany; Mahmoud El-Shahat; Arshi Naqvi; Eman Assirey
Journal:  Molecules       Date:  2018-10-06       Impact factor: 4.411
  6 in total

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