Literature DB >> 6427650

Calcium chelators enhance the efflux of taurine from brain slices.

E R Korpi, S S Oja.   

Abstract

Efflux of exogenous [3H]taurine from superfused slices of cerebral cortex of rat was enhanced by the calcium chelators EDTA and EGTA and by large concentrations of unlabelled taurine and histidine. The enhancement by EDTA and EGTA could be totally blocked by excess calcium, but that by the amino acids only partially. The enhancement of spontaneous taurine release in the absence of calcium complicates the assessment of the calcium dependence of evoked taurine release.

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Year:  1984        PMID: 6427650     DOI: 10.1016/0028-3908(84)90202-8

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN: 0028-3908            Impact factor:   5.250


  3 in total

1.  Depolarization of the neuronal membrane caused by cotransport of taurine and sodium.

Authors:  I Holopainen; E Lidén; A Nilsson; A Sellström
Journal:  Neurochem Res       Date:  1990-01       Impact factor: 3.996

2.  Release of preloaded taurine and hypotaurine from astrocytes in primary culture: stimulation by calcium-free media.

Authors:  I Holopainen; P Kontro; S S Oja
Journal:  Neurochem Res       Date:  1985-01       Impact factor: 3.996

3.  Characteristics of hippocampal glycine release in cell-damaging conditions in the adult and developing mouse.

Authors:  P Saransaari; S S Oja
Journal:  Neurochem Res       Date:  2001-07       Impact factor: 3.996

  3 in total

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