| Literature DB >> 6427649 |
Abstract
The transport of GABA through the microdissected plasma membrane Deiters' neurone reflects the physiological event of postsynaptic uptake of GABA by its uptake carrier. Sodium valproate at concentrations greater than or equal to 2.4 mM was able to decrease markedly (57%) such a transport. This effect, which reduces the efficiency of the GABA postsynaptic inactivation process, might be a mechanism for the potentiation by valproate of the synaptic action of GABA.Entities:
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Year: 1984 PMID： 6427649 DOI： 10.1016/0028-3908(84)90193-x
Source DB: PubMed Journal: Neuropharmacology ISSN： 0028-3908 Impact factor: 5.250