Literature DB >> 6427002

Ionophoric activity of the antibiotic X.14547 A in the mitochondrial membrane.

J Guyot, G Jeminet, R Debise.   

Abstract

Release of Ca++, Mg++ and K+ by the carboxylic ionophore X-14547 A was studied in the mitochondrial membrane. A comparison was made with A.23187 ( Calcimycin ) and X.537 A (Lasalocid A) under the same experimental conditions. It was shown that in this test system X.14547 A is primarily a K+ carrier comparable with X.537 A.

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Year:  1984        PMID： 6427002     DOI： 10.1007/bf01982325

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  3 in total

1.  X-14547A, a new ionophorous antibiotic produced by Streptomyces antibioticus NRRL 8167. Discovery, fermentation, biological properties and taxonomy of the producing culture.

Authors:  C M Liu; T E Hermann; M Liu; D N Bull; N J Palleroni; B L Prosser; J W Westley; P A Miller
Journal:  J Antibiot (Tokyo)       Date:  1979-02       Impact factor: 2.649

2.  Monovalent cation conductance in liposomes induced by ionophore A23187.

Authors:  K S Pyant; G P Brierley
Journal:  Experientia       Date:  1982-10-15

3.  Isolation and characterization of antibiotic X-14547A, a novel monocarboxylic acid ionophore produced by Streptomyces antibioticus NRRL 8167.

Authors:  J W Westley; R H Evans; L H Sello; N Troupe; C M Liu; J F Blount
Journal:  J Antibiot (Tokyo)       Date:  1979-02       Impact factor: 2.649
  3 in total

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