Literature DB >> 6426840

Valproic acid and congenital malformations. A case report.

E W Bantz.   

Abstract

An infant exposed in utero to valproic acid was born with multiple congenital malformations, including duodenal atresia, lumbar vertebral fusion, thoracolumbar scoliosis, renal abnormalities, diastasis recti abdominis, depigmentation of the eyebrows, and a large hemangioma. The child had neonatal hyperbilirubinemia and postnatal growth deficiency. This case report is an addition to the literature implicating valproic acid as a human teratogen.

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Year:  1984        PMID: 6426840     DOI: 10.1177/000992288402300611

Source DB:  PubMed          Journal:  Clin Pediatr (Phila)        ISSN: 0009-9228            Impact factor:   1.168


  7 in total

Review 1.  Environmental aspects of congenital scoliosis.

Authors:  Zheng Li; Xin Yu; Jianxiong Shen
Journal:  Environ Sci Pollut Res Int       Date:  2015-01-29       Impact factor: 4.223

2.  Behavioral teratogenicity of valproic acid: selective effects on behavior after prenatal exposure to rats.

Authors:  C V Vorhees
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 3.  Congenital and idiopathic scoliosis: clinical and genetic aspects.

Authors:  Philip F Giampietro; Robert D Blank; Cathleen L Raggio; Sajid Merchant; F Stig Jacobsen; Thomas Faciszewski; Sanjay K Shukla; Anne R Greenlee; Cory Reynolds; David B Schowalter
Journal:  Clin Med Res       Date:  2003-04

4.  Omphalocele in a newborn baby exposed to sodium valproate in utero.

Authors:  T Boussemart; D Bonneau; G Levard; M Berthier; D Oriot
Journal:  Eur J Pediatr       Date:  1995-03       Impact factor: 3.183

5.  Vitamin A deficiency induces congenital spinal deformities in rats.

Authors:  Zheng Li; Jianxiong Shen; William Ka Kei Wu; Xiaojuan Wang; Jinqian Liang; Guixing Qiu; Jiaming Liu
Journal:  PLoS One       Date:  2012-10-05       Impact factor: 3.240

6.  Congenital scoliosis in monozygotic twins: case report and review of possible factors contributing to its development.

Authors:  Angelos Kaspiris; Theodoros B Grivas; Hans-Rudolf Weiss
Journal:  Scoliosis       Date:  2008-11-18

7.  Congenital Kyphoscoliosis in Monozygotic Twins: Ten-Year Follow-up Treated by Posterior Vertebral Column Resection (PVCR): A Case Report.

Authors:  Dong-Gune Chang; Jae Hyuk Yang; Jung-Hee Lee; Young-Hoon Kim; Jin-Hyok Kim; Seung-Woo Suh; Kee-Yong Ha; Se-Il Suk
Journal:  Medicine (Baltimore)       Date:  2016-04       Impact factor: 1.889

  7 in total

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