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Literature DB >> 6426513

Studies of Fe3+ transport across isolated intestinal brush-border membrane of the mouse.

Abstract

Mouse intestinal brush-border membrane vesicles take up iron from media containing 59Fe3 +-nitrilotriacetic acid. The iron uptake by the vesicles represents accumulation of iron which relates to an osmotically active space. Uptake is linearly related to vesicle protein concentration and is inhibited by low incubation temperature and low medium free Fe3+ concentrations. Experiments with the lipid soluble iron ligand 8-hydroxyquinoline and with Triton X-100 imply that the uptake is rate limited by membrane transport.

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Year: 1984 PMID： 6426513 DOI： 10.1016/0005-2736(84)90047-6

Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002

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Cited

7 in total

1. Alterations in the mucosal processing of iron in response to very-short-term dietary iron depletion and repletion.

Authors: R W Topham; C E Eads; B F Butler
Journal: Biochem J Date: 1992-06-15 Impact factor: 3.857

2. Role of labile iron in the toxicity of pharmacological ascorbate.

Authors: Juan Du; Brett A Wagner; Garry R Buettner; Joseph J Cullen
Journal: Free Radic Biol Med Date: 2015-04-07 Impact factor: 7.376

3. Iron uptake by human upper small intestine microvillous membrane vesicles. Indication for a facilitated transport mechanism mediated by a membrane iron-binding protein.

Authors: R Teichmann; W Stremmel
Journal: J Clin Invest Date: 1990-12 Impact factor: 14.808

4. The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract.

Authors: R J Playford; A M Hanby; S Gschmeissner; L P Peiffer; N A Wright; T McGarrity
Journal: Gut Date: 1996-08 Impact factor: 23.059

Studies of Fe3+ transport across isolated intestinal brush-border membrane of the mouse.

1. Alterations in the mucosal processing of iron in response to very-short-term dietary iron depletion and repletion.

2. Role of labile iron in the toxicity of pharmacological ascorbate.

3. Iron uptake by human upper small intestine microvillous membrane vesicles. Indication for a facilitated transport mechanism mediated by a membrane iron-binding protein.

4. The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract.

5. Absorption of iron from ferritin is independent of heme iron and ferrous salts in women and rat intestinal segments.

6. Iron absorption in the iron-deficient rat.

7. Dependence of intestinal iron absorption on the valency state of iron.