Literature DB >> 6425076

Effect of insulin on the synthesis and release of lipid peroxide by cultured hepatocytes isolated from normal and diabetic rats.

K Kosugi, Y Harano, A Kashiwagi, M Suzuki, Y Shigeta.   

Abstract

Lipid peroxide content in hepatocytes isolated from ketotic diabetic rats was higher than normal, and the release of peroxide into the media was also elevated for the initial 18 h. Insulin suppressed both peroxide release and synthesis by cultured hepatocytes isolated from normal and from diabetic rats.

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Year:  1984        PMID: 6425076     DOI: 10.1007/bf01952571

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  14 in total

1.  A simple fluorometric assay for lipoperoxide in blood plasma.

Authors:  K Yagi
Journal:  Biochem Med       Date:  1976-04

2.  Lipid peroxide level in plasma of diabetic patients.

Authors:  Y Sato; N Hotta; N Sakamoto; S Matsuoka; N Ohishi; K Yagi
Journal:  Biochem Med       Date:  1979-02

3.  Metabolism of isolated fat cells. 3. The similar inhibitory action of phospholipase C (Clostridium perfringens alpha toxin) and of insulin on lipolysis stimulated by lipolytic hormones and theophylline.

Authors:  M Rodbell; A B Jones
Journal:  J Biol Chem       Date:  1966-01-10       Impact factor: 5.157

4.  Fatty acid oxidation, oxidative phosphorylation and ultrastructure of mitochondria in the diabetic rat liver. Hepatic factors in diabetic ketosis.

Authors:  Y Harano; R G DePalma; L Lavine; M Miller
Journal:  Diabetes       Date:  1972-05       Impact factor: 9.461

5.  Rat liver glucose 6-phosphate dehydrogenase. Regulation by carbohydrate diet and insulin.

Authors:  D Rudack; E M Chisholm; D Holten
Journal:  J Biol Chem       Date:  1971-03-10       Impact factor: 5.157

6.  The consequences of lipid peroxidation in isolated hepatocytes.

Authors:  J Högberg; P Moldéus; B Arborgh; P J O'Brien; S Orrenius
Journal:  Eur J Biochem       Date:  1975-11-15

7.  Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

Authors:  D W Morel; J R Hessler; G M Chisolm
Journal:  J Lipid Res       Date:  1983-08       Impact factor: 5.922

8.  Effect of polyunsaturated fatty acids and antioxidants on lipid peroxidation in tissue cultures.

Authors:  V C Gavino; J S Miller; S O Ikharebha; G E Milo; D G Cornwell
Journal:  J Lipid Res       Date:  1981-07       Impact factor: 5.922

9.  Lipoperoxide level of the retina of chick embryo exposed to high concentration of oxygen.

Authors:  K Yagi; S Matsuoka; H Ohkawa; N Ohishi; Y K Takeuchi; H Sakai
Journal:  Clin Chim Acta       Date:  1977-10-15       Impact factor: 3.786

10.  Effect of insulin on ultrastructure and glycogenesis in primary cultures of adult rat hepatocytes.

Authors:  D Bernaert; J C Wanson; P Drochmans; A Popowski
Journal:  J Cell Biol       Date:  1977-09       Impact factor: 10.539

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