Literature DB >> 6424932

Treatment of implanted peritoneal cancer in rats by continuous hyperthermic peritoneal perfusion in combination with an anticancer drug.

S Koga, R Hamazoe, M Maeta, N Shimizu, H Kanayama, Y Osaki.   

Abstract

To study the feasibility of combined hyperthermic and anticancer drug treatment for peritoneal cancer, we devised a continuous hyperthermic peritoneal perfusion system in combination with mitomycin C. The model uses i.p.-transplantable rat ascites hepatoma 100B cells. Hyperthermic peritoneal perfusion alone or combined with mitomycin C was performed after i.p. inoculation of the tumor cells into rats. In rats treated with combined peritoneal perfusion (41.5 degrees) and mitomycin C, the mean survival times were significantly prolonged as compared to those of rats treated with peritoneal perfusion at 41.5 degrees alone. Our results suggest that combined hyperthermic peritoneal perfusion and mitomycin C treatment may represent a therapeutic and prophylactic treatment for peritoneal metastasis after gastric cancer surgery in humans.

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Year:  1984        PMID： 6424932

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  18 in total

Review 1.  Management of peritoneal carcinomatosis from colorectal cancer.

Authors:  Chukwuemeka U Ihemelandu; Perry Shen; John H Stewart; Konstantinos Votanopoulos; Edward A Levine
Journal:  Semin Oncol       Date:  2011-08       Impact factor: 4.929

Review 2.  Peritoneal Metastases from Gastrointestinal Cancer.

Authors:  Paul H Sugarbaker
Journal:  Curr Oncol Rep       Date:  2018-06-08       Impact factor: 5.075

3.  Prevention and Treatment of Peritoneal Metastases: a Comprehensive Review.

Authors:  Paul H Sugarbaker
Journal:  Indian J Surg Oncol       Date:  2019-01-03

4.  Recommendations in the management of epithelial appendiceal neoplasms and peritoneal dissemination from mucinous tumours (pseudomyxoma peritonei).

Authors:  P Barrios; F Losa; S Gonzalez-Moreno; A Rojo; A Gómez-Portilla; P Bretcha-Boix; I Ramos; J Torres-Melero; R Salazar; M Benavides; T Massuti; E Aranda
Journal:  Clin Transl Oncol       Date:  2015-10-21       Impact factor: 3.405

Review 5.  Management of peritoneal carcinomatosis from colorectal cancer: review of the literature.

Authors:  Carlo Vallicelli; Davide Cavaliere; Fausto Catena; Federico Coccolini; Luca Ansaloni; Elia Poiasina; Hariscine K Abongwa; Belinda De Simone; Laura Alberici; Massimo Framarini; Giorgio M Verdecchia
Journal:  Int J Colorectal Dis       Date:  2014-06-11       Impact factor: 2.571

6.  Metastatic colorectal cancer: survival comparison of hepatic resection versus cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Authors:  Aaron U Blackham; Gregory B Russell; John H Stewart; Konstantinos Votanopoulos; Edward A Levine; Perry Shen
Journal:  Ann Surg Oncol       Date:  2014-03-11       Impact factor: 5.344

Review 7.  Cytoreductive surgery and intraperitoneal chemotherapy for treatment of peritoneal carcinomatosis from colorectal origin.

Authors:  F Losa; P Barrios; R Salazar; J Torres-Melero; M Benavides; T Massuti; I Ramos; E Aranda
Journal:  Clin Transl Oncol       Date:  2013-06-06       Impact factor: 3.405

8.  Surgical management of carcinomatosis from colorectal cancer.

Authors:  Paul H Sugarbaker
Journal:  Clin Colon Rectal Surg       Date:  2005-08

9.  Treatment of malignant peritoneal effusion in digestive and ovarian cancer.

Authors:  F N Gilly; P Y Carry; A Brachet; A C Sayag; G Panteix; B Salle; J Bienvenu; V Banssillon; G Burgard; M Manchon
Journal:  Med Oncol Tumor Pharmacother       Date:  1992

10.  Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination.

Authors:  Y Yonemura; T Fujimura; S Fushida; S Takegawa; T Kamata; K Katayama; T Kosaka; A Yamaguchi; K Miwa; I Miyazaki
Journal:  World J Surg       Date:  1991 Jul-Aug       Impact factor: 3.352
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