Literature DB >> 6422636

HLA-ABC and DR antigens in celiac disease. A study in a pediatric Italian population.

S Trabace, A Giunta, M Rosso, D Marzorati, I Cascino, A Tettamanti, M C Mazzilli, E Gandini.   

Abstract

HLA phenotypes of 64 Italian pediatric patients with celiac disease (CD) were compared with those of a group of healthy controls. DR3 and DR7 are significantly increased as reported in other populations. In addition an increase of heterozygotes DR5/DR7 was observed in our patients. The Hardy-Weinberg distribution in the patients group shows a disequilibrium due to the genotype DR5/DR7. Our data confirm that more than one HLA gene product is associated with CD: one with DR3 and the other with DR7.

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Year:  1984        PMID: 6422636     DOI: 10.1111/j.1423-0410.1984.tb00059.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


  2 in total

Review 1.  The roles of MHC class II genes and post-translational modification in celiac disease.

Authors:  Ludvig M Sollid
Journal:  Immunogenetics       Date:  2017-07-10       Impact factor: 2.846

2.  Human leucocyte class I and II antigens in coeliac disease: a study in an Austrian paediatric population.

Authors:  B M Winklhofer-Roob; E Rossipal; G Lanzer
Journal:  Eur J Pediatr       Date:  1991-08       Impact factor: 3.183

  2 in total

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