Literature DB >> 6422179

Naloxone does not affect ventilatory responses to hypoxia and hypercapnia in rats.

R A Steinbrook, H A Feldman, V Fencl, V A Forte, R A Gabel, D E Leith, S E Weinberger.   

Abstract

Ventilatory responses (tidal volume, respiratory frequency, and minute ventilation) to steady-state hypoxia and steady-state hypercapnia were measured plethysmographically in awake unrestrained adult rats, before and after subcutaneous injection of placebo (saline) naloxone in doses up to 5.0 mg/kg. Naloxone did not alter the ventilatory responses to hypoxia or hypercapnia.

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Year:  1984        PMID: 6422179     DOI: 10.1016/0024-3205(84)90205-4

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  1 in total

1.  Opioid depression of respiration in neonatal rats.

Authors:  J J Greer; J E Carter; Z al-Zubaidy
Journal:  J Physiol       Date:  1995-06-15       Impact factor: 5.182

  1 in total

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