Literature DB >> 6421784

Usefulness of postoperative hip irradiation in the prevention of heterotopic bone formation in a high risk group of patients.

I MacLennan, H M Keys, C M Evarts, P Rubin.   

Abstract

Heterotopic ossification is a complication of total hip arthroplasty in 14 to 30% of patients. Significant functional impairment will occur in up to 28% of patients with ectopic bone. The high risk group includes those with preexisting heterotopic bone in either hip, those suffering from hypertrophic osteoarthritis or ankylosing spondylitis and patients who have had multiple procedures on the hip. Fifty-eight patients (67 hips) were irradiated after surgical removal of ectopic bone (53 hips) or received radiation prophylaxis of heterotopic ossification (14 hips). Ninety-five percent of patients had either no bone visible or insignificant amounts of ectopic bone visible on postoperative hip X-rays. Only 5% of patients showed significant persistence of ectopic bone. Postoperative hip function was dramatically improved compared to preoperative function in all patients treated. The importance of early commencement of irradiation is emphasized.

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Year:  1984        PMID: 6421784     DOI: 10.1016/0360-3016(84)90411-5

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  12 in total

1.  The suppression of heterotopic ossification after total hip arthroplasty.

Authors:  H J Reis; W Küsswetter; T Schellinger
Journal:  Int Orthop       Date:  1992       Impact factor: 3.075

2.  Para-articular ossification in total hip replacement: an indication for irradiation therapy.

Authors:  R Brunner; E Morscher; R Hünig
Journal:  Arch Orthop Trauma Surg       Date:  1987

3.  Radiotherapy in the prevention of recurrence of paraarticular ossification in total hip prostheses.

Authors:  G J van der Werf; N G van Hasselt; A J Tonino
Journal:  Arch Orthop Trauma Surg       Date:  1985

4.  The effect of late radiotherapy on the progression of heterotopic ossification following total hip arthroplasty.

Authors:  Mina Morcos; Karen Smith; Michael Tanzer
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-03-21

5.  [Prospective study on the prevention of heterotopic ossification after total hip replacement. Non-steroidal anti-inflammatory agents versus radiation therapy].

Authors:  O Kölbl; M Flentje; J Eulert; T Barthel; D Knelles; U Kraus
Journal:  Strahlenther Onkol       Date:  1997-12       Impact factor: 3.621

6.  [Effect of a calcium inhibitor, verapamil, on the development of heterotopic ossifications. An experimental study in rats].

Authors:  J Duriez; B Flautre; M C Blary; R Duriez
Journal:  Int Orthop       Date:  1990       Impact factor: 3.075

7.  Heterotopic ossification after total hip arthroplasty (THA) in congenital hip disease: comparison of two different prophylactic protocols.

Authors:  E E Pakos; K S Stafilas; A N Politis; P G Tsekeris; G Mitsionis; T A Xenakis
Journal:  Clin Transl Oncol       Date:  2009-02       Impact factor: 3.405

8.  Prevention of heterotopic ossification in hip arthroplasties by means of an early single-dose radiotherapy (6 Gy).

Authors:  P Schai; R Brunner; E Morscher; K H Schubert
Journal:  Arch Orthop Trauma Surg       Date:  1995       Impact factor: 3.067

9.  Prevention of periarticular heterotopic ossification following total hip arthroplasty. Clinical experience with indomethacin and ibuprofen.

Authors:  B Sodemann; P E Persson; O S Nilsson
Journal:  Arch Orthop Trauma Surg       Date:  1988

10.  Low-dose external beam radiotherapy as a postoperative treatment for patients with diffuse pigmented villonodular synovitis of the knee: 4 recurrences in 23 patients followed for mean 9 years.

Authors:  Geumju Park; Young Seok Kim; Jong Hoon Kim; Sang-wook Lee; Si Yeol Song; Eun Kyung Choi; Seong Yoon Yi; Seung Do Ahn
Journal:  Acta Orthop       Date:  2012-04-11       Impact factor: 3.717

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