| Literature DB >> 6421752 |
J M Bolster, W Vaalburg, W Van Veen, T Van Dijk, H D Van der Molen, H Wynberg, M G Woldring.
Abstract
No-carrier-added DL-[1-11C]-DOPA has been synthesized by carboxylation of an alpha-lithioisocyanide with a radiochemical yield of up to 15% without correction for decay. The total synthesis time is 30 min. The resolution of the D- and L-isomers was accomplished within 16 min by HPLC using a chiral stationary phase and a phosphate buffer of pH 4.5 as eluent.Entities:
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Year: 1983 PMID： 6421752 DOI： 10.1016/0020-708x(83)90019-4
Source DB: PubMed Journal: Int J Appl Radiat Isot ISSN： 0020-708X