Literature DB >> 6421519

Isotype of lytic antibodies in serum of Chagas' disease patients.

S A Romeiro, H A Takehara, I Mota.   

Abstract

The isotype of anti-Trypanosoma cruzi lytic antibodies present in sera obtained from patients with the chronic phase of Chagas' disease was determined. Serum samples were submitted to gel filtration in Sephacryl S-200, ion exchange chromatography in DEAE-cellulose, affinity chromatography with protein A and immunoadsorption with anti-human IgG-Sepharose. The results of these experiments showed that human anti-T. cruzi lytic antibodies are mainly located in the IgG isotype probably in the IgG1 and IgG2 subclasses.

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Year:  1984        PMID： 6421519      PMCID： PMC1535813     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  12 in total

Review 1.  Immunity to Trypanosoma cruzi.

Authors:  Z Brener
Journal:  Adv Parasitol       Date:  1980       Impact factor: 3.870

2.  Mechanisms of resistance against experimental Trypanosoma cruzi infection: the importance of antibodies and antibody-forming capacity in the Biozzi high and low responder mice.

Authors:  F Kierszenbaum; J G Howard
Journal:  J Immunol       Date:  1976-05       Impact factor: 5.422

3.  Cell-mediated cytotoxicity to Trypanosoma cruzi. I. Antibody-dependent cell mediated cytotoxicity to trypomastigote bloodstream forms.

Authors:  K Okabe; T L Kipnis; V L Calich; W Dias da Silva
Journal:  Clin Immunol Immunopathol       Date:  1980-07

4.  Trypanosoma cruzi: role of different antibody classes in protection against infection in the mouse.

Authors:  H A Takehara; A Perini; M H da Silva; I Mota
Journal:  Exp Parasitol       Date:  1981-08       Impact factor: 2.011

5.  Protective effects of specific antibodies in Trypanosoma cruzi infections.

Authors:  A U Krettli; Z Brener
Journal:  J Immunol       Date:  1976-03       Impact factor: 5.422

6.  Passive immunization of mice against Trypanosoma cruzi using convalescent mouse serum.

Authors:  N McHardy
Journal:  Tropenmed Parasitol       Date:  1977-06

7.  75Se-methionine labelled Trypanosoma cruzi blood trypomastigotes: opsonization by chronic infection serum facilitates killing in spleen and liver.

Authors:  M T Scott; L Moyes
Journal:  Clin Exp Immunol       Date:  1982-06       Impact factor: 4.330

8.  Effects of complement depletion in experimental chagas disease: immune lysis of virulent blood forms of Trypanosoma cruzi.

Authors:  D B Budzko; M C Pizzimenti; F Kierszenbaum
Journal:  Infect Immun       Date:  1975-01       Impact factor: 3.441

9.  Trypanosoma cruzi infection in B-cell-deficient rats.

Authors:  A M Rodriguez; F Santoro; D Afchain; H Bazin; A Capron
Journal:  Infect Immun       Date:  1981-02       Impact factor: 3.441

10.  Resistance against Trypanosoma cruzi associated to anti-living trypomastigote antibodies.

Authors:  A U Krettli; Z Brener
Journal:  J Immunol       Date:  1982-05       Impact factor: 5.422
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  5 in total

1.  Purification of a Trypanosoma cruzi membrane glycoprotein which elicits lytic antibodies.

Authors:  K A Norris; G Harth; M So
Journal:  Infect Immun       Date:  1989-08       Impact factor: 3.441

2.  Restricted IgG isotype profiles in T. cruzi infected mice and Chagas' disease patients.

Authors:  M T Scott; M Goss-Sampson
Journal:  Clin Exp Immunol       Date:  1984-11       Impact factor: 4.330

3.  Human and mouse sera recognize the same polypeptide associated with immunological resistance to Trypanosoma cruzi infection.

Authors:  M S Martins; L Hudson; A U Krettli; J R Cançado; Z Brener
Journal:  Clin Exp Immunol       Date:  1985-08       Impact factor: 4.330

4.  Chagas' disease: IgG isotypes against cytoplasmic (CRA) and flagellar (FRA) recombinant repetitive antigens of Trypanosoma cruzi in chronic Chagasic patients.

Authors:  A F A Verçosa; V M B Lorena; C L Carvalho; M F A D Melo; M G A Cavalcanti; E D Silva; A G P Ferreira; V R A Pereira; W V Souza; Y M Gomes
Journal:  J Clin Lab Anal       Date:  2007       Impact factor: 2.352

5.  The World Health Organization and Immunology Research and Training, 1961-1974.

Authors:  R Hankins
Journal:  Med Hist       Date:  2001-04       Impact factor: 1.419
  5 in total

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