Literature DB >> 6421251

Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men.

T J Flotte, V A Hatcher, A E Friedman-Kien.   

Abstract

This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

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Year:  1984        PMID: 6421251

Source DB:  PubMed          Journal:  Arch Dermatol        ISSN: 0003-987X


  7 in total

1.  AIDS-related Kaposi's sarcoma displays differential expression of endothelial surface antigens.

Authors:  P A Scully; H K Steinman; C Kennedy; K Trueblood; D M Frisman; J R Voland
Journal:  Am J Pathol       Date:  1988-02       Impact factor: 4.307

2.  Evidence for the origin of Kaposi's sarcoma from lymphatic endothelium.

Authors:  J H Beckstead; G S Wood; V Fletcher
Journal:  Am J Pathol       Date:  1985-05       Impact factor: 4.307

3.  The expression of endothelial cell surface antigens by AIDS-associated Kaposi's sarcoma. Evidence for a vascular endothelial cell origin.

Authors:  J L Rutgers; R Wieczorek; F Bonetti; K L Kaplan; D N Posnett; A E Friedman-Kien; D M Knowles
Journal:  Am J Pathol       Date:  1986-03       Impact factor: 4.307

4.  Infection of human endothelial cells by human T-lymphotropic virus type I.

Authors:  D D Ho; T R Rota; M S Hirsch
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

5.  HIV infection of human gastrointestinal submucosal cells: an in vitro model that mimics Kaposi's sarcoma.

Authors:  M P Moyer; A Ramirez; A Woolf; R I Huot; M S McKee-Suarez
Journal:  In Vitro Cell Dev Biol       Date:  1991-04

Review 6.  Human herpesvirus-8: detection of novel herpesvirus-like DNA sequences in Kaposi's sarcoma and other lesions.

Authors:  O M Memar; P L Rady; S K Tyring
Journal:  J Mol Med (Berl)       Date:  1995-12       Impact factor: 4.599

7.  Factor-XIIIa-expressing dermal dendrocytes in Kaposi's sarcoma. A comparison between classical and immunosuppression-associated types.

Authors:  J Kanitakis; M Roca-Miralles
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992
  7 in total

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