Literature DB >> 6421061

Retinoic acid enhances the growth of only one subpopulation of granulomonocyte precursors.

M Aglietta, W Piacibello, F Sanavio, A Visconti, F Gavosto.   

Abstract

The effect of various concentrations of retinoic acid on the growth of committed granulomonopoietic precursors (CFU-GM) was studied on semisolid agar cultures. Retinoic acid increased the growth of day 14 CFU-GM but had no significant effect on day 7 CFU-GM. Since the latter are believed to represent the progeny of day 14 CFU-GM it is suggested that the effect of retinoic acid is confined to the early stages of granulomonocytic differentiation.

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Year:  1984        PMID: 6421061     DOI: 10.1159/000206564

Source DB:  PubMed          Journal:  Acta Haematol        ISSN: 0001-5792            Impact factor:   2.195


  1 in total

1.  Roles of retinoids and retinoic Acid receptors in the regulation of hematopoietic stem cell self-renewal and differentiation.

Authors:  Louise E Purton
Journal:  PPAR Res       Date:  2007       Impact factor: 4.964

  1 in total

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