Literature DB >> 6420708

The molecular biology of immunoglobulin D.

F R Blattner, P W Tucker.   

Abstract

Immunoglobulin D (IgD) is co-expressed with immunoglobulin M (IgM) on the membranes of most B cells, yet its biological function has remained a mystery. Recent detailed information on the structure and transcription of the unusual IgD heavy chain (delta) gene in mouse suggests a complex genetic control. A model is presented for the developmental regulation of IgM and IgD and roles suggested for the membrane and secreted forms of IgD in the immune network.

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Year:  1984        PMID： 6420708     DOI： 10.1038/307417a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  46 in total

Review 1.  Immunoglobulin D: properties, measurement, and clinical relevance.

Authors:  A O Vladutiu
Journal:  Clin Diagn Lab Immunol       Date:  2000-03

2.  Immunological studies in the hyper-immunoglobulin D syndrome.

Authors:  A Haraldsson; C M Weemaes; A W De Boer; J A Bakkeren; G B Stoelinga
Journal:  J Clin Immunol       Date:  1992-11       Impact factor: 8.317

3.  An RNA polymerase pause site is associated with the immunoglobulin mus poly(A) site.

Authors:  Martha L Peterson; Shannon Bertolino; Frankie Davis
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

Review 4.  The enigmatic function of IgD: some answers at last.

Authors:  Cindy Gutzeit; Kang Chen; Andrea Cerutti
Journal:  Eur J Immunol       Date:  2018-06-12       Impact factor: 5.532

5.  Hybridohistochemical demonstration of alternative splicing of the CALC-I gene.

Authors:  M Denijn; R A De Weger; C J Lips; J A Van Unnik; W Den Otter
Journal:  Am J Pathol       Date:  1991-02       Impact factor: 4.307

6.  Regulated production of mu m and mu s mRNA requires linkage of the poly(A) addition sites and is dependent on the length of the mu s-mu m intron.

Authors:  M L Peterson; R P Perry
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

7.  Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome.

Authors:  M Nolan-Willard; M T Berton; P Tucker
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205

8.  The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice.

Authors:  M L Peterson; R P Perry
Journal:  Mol Cell Biol       Date:  1989-02       Impact factor: 4.272

9.  Assessment of antigen-specific receptor function of surface immunoglobulin M and D with identical hapten specificity.

Authors:  R Tisch; M Watanabe; M Letarte; N Hozumi
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

10.  Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA.

Authors:  N Tsurushita; N M Avdalovic; L J Korn
Journal:  Nucleic Acids Res       Date:  1987-06-11       Impact factor: 16.971
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