Literature DB >> 6420698

Induction and selection of drug resistant mutants of Plasmodium falciparum.

J Inselburg.   

Abstract

Conditions for mutagenizing Plasmodium falciparum in culture with the mutagen N-methyl-N'-nitro-N-nitrosoguanidine have been established. Parasite mutants resistant to aphidicolin, cycloheximide and sinefungin have been selected and subcloned.

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Year:  1984        PMID： 6420698     DOI： 10.1016/0166-6851(84)90021-5

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  3 in total

1.  Genetic mapping reveals that sinefungin resistance in Toxoplasma gondii is controlled by a putative amino acid transporter locus that can be used as a negative selectable marker.

Authors:  Michael S Behnke; Asis Khan; L David Sibley
Journal:  Eukaryot Cell       Date:  2014-12-05

2.  Development of halofantrine resistance and determination of cross-resistance patterns in Plasmodium falciparum.

Authors:  M Nateghpour; S A Ward; R E Howells
Journal:  Antimicrob Agents Chemother       Date:  1993-11       Impact factor: 5.191

3.  Sinefungin resistance of Saccharomyces cerevisiae arising from Sam3 mutations that inactivate the AdoMet transporter or from increased expression of AdoMet synthase plus mRNA cap guanine-N7 methyltransferase.

Authors:  Sushuang Zheng; Stewart Shuman; Beate Schwer
Journal:  Nucleic Acids Res       Date:  2007-10-11       Impact factor: 16.971
  3 in total

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