Literature DB >> 6420444

Paradoxical responsiveness of growth hormone to corticotropin-releasing factor in acromegaly.

G F Pieters, A R Hermus, A G Smals, P W Kloppenborg.   

Abstract

Corticotropin-releasing factor elicited an increase in serum GH in two of six patients with acromegaly. Both patients also responded paradoxically to LHRH administration and one of them also to TRH, further illustrating the dedifferentiation of the receptors of the somatotrophs in acromegaly.

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Year:  1984        PMID: 6420444     DOI: 10.1210/jcem-58-3-560

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


  4 in total

1.  In vivo labeling with1251-CRH of human ACTH-producing pituitary adenomas heterotransplanted to nude mice.

Authors:  Uirich J Knappe; Dieter K Lüdecke; Maximilian J A Puchner; Wolfgang Saeger; Hans-D Herrmann
Journal:  Endocr Pathol       Date:  1991-12       Impact factor: 3.943

2.  Plasma growth hormone (GH) responses to corticotropin-releasing hormone in patients with acromegaly--the effect of dexamethasone pretreatment and the comparison with GH responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and GH-releasing hormone.

Authors:  A Utsumi; K Hanew; A Sugawara; Y Shimizu; O Murakami; H Ikeda; K Yoshinaga
Journal:  J Endocrinol Invest       Date:  1992-03       Impact factor: 4.256

Review 3.  Psychoneuroendocrine research in depression. II. Hormonal responses to releasing hormones as a probe for hypothalamic-pituitary-endorgan dysfunction.

Authors:  K P Lesch; R Rupprecht
Journal:  J Neural Transm       Date:  1989       Impact factor: 3.575

4.  Corticotropin- and growth hormone-releasing factor (CRF and GRF) in the diagnosis of hypothalamo-pituitary diseases.

Authors:  K von Werder; O A Müller
Journal:  Neurosurg Rev       Date:  1985       Impact factor: 3.042

  4 in total

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