Literature DB >> 6418330

Striatal dopamine metabolism in living monkeys examined by positron emission tomography.

S Garnett, G Firnau, C Nahmias, R Chirakal.   

Abstract

Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This is the first time that the regional distribution of a neurotransmitter has been demonstrated in monkeys.

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Year:  1983        PMID： 6418330     DOI： 10.1016/0006-8993(83)91187-3

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  19 in total

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