Literature DB >> 6418146

Metabolism of malonic semialdehyde in man.

R D Scholem, G K Brown.   

Abstract

Malonic semialdehyde is formed in the alternative pathway of propionate metabolism and in the catabolism of beta-alanine. Studies of these pathways in cultured cells from a patient with mitochondrial malonyl-CoA decarboxylase deficiency indicate that malonic semialdehyde is directly converted into acetyl-CoA in man.

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Year:  1983        PMID： 6418146      PMCID： PMC1152472          DOI： 10.1042/bj2160081

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  15 in total

1.  The catabolism of C14-labeled beta-alanine in the intact rat.

Authors:  A PIHL; P FRITZSON
Journal:  J Biol Chem       Date:  1955-07       Impact factor: 5.157

2.  Degradation of malonic acid by rat tissues.

Authors:  H I NAKADA; J B WOLFE; A N WICK
Journal:  J Biol Chem       Date:  1957-05       Impact factor: 5.157

3.  The enzymatic synthesis of beta-aminoisobutyrate, a product of valine metabolism, and of beta-alanine, a product of beta-hydroxypropionate metabolism.

Authors:  F P KUPIECKI; M J COON
Journal:  J Biol Chem       Date:  1957-12       Impact factor: 5.157

4.  Metabolism of propionic acid in animal tissues. I. Enzymatic conversion of propionate to succinate.

Authors:  M FLAVIN; S OCHOA
Journal:  J Biol Chem       Date:  1957-12       Impact factor: 5.157

5.  Transamination of gamma-aminobutyric acid and beta-alanine in brain and liver.

Authors:  E ROBERTS; H M BREGOFF
Journal:  J Biol Chem       Date:  1953-03       Impact factor: 5.157

6.  A simple incubation flask for 14CO2 collection.

Authors:  R M Fox
Journal:  Anal Biochem       Date:  1971-06       Impact factor: 3.365

7.  Properties of malonyl-CoA decarboxylase and its relation with malonyl-CoA incorporation into fatty acids by rat liver mitochondria.

Authors:  C Landriscina; G V Gnoni; E Quagliariello
Journal:  Eur J Biochem       Date:  1971-04-30

8.  Malonate metabolism in rat brain mitochondria.

Authors:  A H Koeppen; E J Mitzen; A A Ammoumi
Journal:  Biochemistry       Date:  1974-08-13       Impact factor: 3.162

9.  3-hydroxypropionate: significance of -oxidation of propionate in patients with propionic acidemia and methylmalonic acidemia.

Authors:  T Ando; K Rasmussen; W L Nyhan; D Hull
Journal:  Proc Natl Acad Sci U S A       Date:  1972-10       Impact factor: 11.205

10.  Enzymatic hydrolysis of the coenzyme a thiol esters of beta-hydroxypropionic and beta-hydroxyisobutyric acids.

Authors:  G RENDINA; M J COON
Journal:  J Biol Chem       Date:  1957-03       Impact factor: 5.157
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  6 in total

1.  Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism.

Authors:  Kirkland A Wilson; Yong Han; Miaoqi Zhang; Jeremy P Hess; Kimberly A Chapman; Gary W Cline; Gregory P Tochtrop; Henri Brunengraber; Guo-Fang Zhang
Journal:  Am J Physiol Endocrinol Metab       Date:  2017-06-20       Impact factor: 4.310

2.  Tracer studies of the interconversion of R- and S-methylmalonic semialdehydes in man.

Authors:  N J Manning; R J Pollitt
Journal:  Biochem J       Date:  1985-10-15       Impact factor: 3.857

3.  Membranes as Structural Antioxidants: RECYCLING OF MALONDIALDEHYDE TO ITS SOURCE IN OXIDATION-SENSITIVE CHLOROPLAST FATTY ACIDS.

Authors:  Emanuel Schmid-Siegert; Olga Stepushenko; Gaetan Glauser; Edward E Farmer
Journal:  J Biol Chem       Date:  2016-05-03       Impact factor: 5.157

4.  The metabolism of tetradecylthiopropionic acid, a 4-thia stearic acid, in the rat. In vivo and in vitro studies.

Authors:  E Hvattum; S Skrede; J Bremer; M Solbakken
Journal:  Biochem J       Date:  1992-09-15       Impact factor: 3.857

Review 5.  Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.

Authors:  Caitlyn E Bowman; Michael J Wolfgang
Journal:  Adv Biol Regul       Date:  2018-09-05

6.  The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA.

Authors:  Eunsook S Jin; Min H Lee; Craig R Malloy
Journal:  Metabol Open       Date:  2021-02-26
  6 in total

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