Literature DB >> 6414839

A preliminary report: preparations containing Interleukin-3 (IL-3) promote proliferation of multipotential stem cells (CFUs) in the mouse.

J M Garland, S Crompton.   

Abstract

The effect of a preparation containing the lymphokine "Interleukin-3" (IL-3) on murine marrow CFUs has been investigated. When marrow cells are incubated for a short period with IL-3 in vitro, the number of spleen colonies that develop upon injection into irradiated recipients is increased. In addition, an increase is seen in the proportion of CFUs killed in vitro by tritiated thymidine. IL-3 does not affect the seeding efficiency of CFUs in the spleen, but appears to act directly on them, not through production of an endogenous marrow stimulator.

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Year:  1983        PMID： 6414839

Source DB:  PubMed          Journal:  Exp Hematol        ISSN： 0301-472X            Impact factor:   3.084


  8 in total

1.  Tumor-promoting phorbol esters support the in vitro proliferation of murine pluripotent hematopoietic stem cells.

Authors:  J L Spivak; B B Hogans; R K Stuart
Journal:  J Clin Invest       Date:  1989-01       Impact factor: 14.808

2.  Dissociation between onset of natural killer E-rosette forming cells and of T3-positive cells following HLA-mismatched T cell depleted bone marrow transplantation.

Authors:  J P De Villartay; F Le Deist; C Griscelli; A Fischer
Journal:  Clin Exp Immunol       Date:  1987-02       Impact factor: 4.330

3.  Hemopoietic growth factor production by a marrow adherent cell line.

Authors:  P J Quesenberry; P D Witte; K Landreth; Z X Song; H E McGrath; F M Stewart; Y X He; G B Baber; E Kleeman; D Innes
Journal:  Trans Am Clin Climatol Assoc       Date:  1986

4.  Rat IL-3 stimulates the growth of rat mucosal mast cells in culture.

Authors:  D M Haig; C McMenamin; J Redmond; D Brown; I G Young; S D Cohen; A J Hapel
Journal:  Immunology       Date:  1988-10       Impact factor: 7.397

5.  Distinct mechanisms may account for the growth-promoting activity of interleukin 3 on cells of lymphoid and myeloid origin.

Authors:  R Palacios; J Garland
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

6.  Interleukin 3 promotes erythroid burst formation in "serum-free" cultures without detectable erythropoietin.

Authors:  J W Goodman; E A Hall; K L Miller; S G Shinpock
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

7.  Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.

Authors:  Li-Hao Huang; Jingang Gui; Erika Artinger; Ruth Craig; Brent L Berwin; Patricia A Ernst; Catherine C Y Chang; Ta-Yuan Chang
Journal:  Arterioscler Thromb Vasc Biol       Date:  2013-07-11       Impact factor: 8.311

8.  Interleukin 3 promotes the in vitro proliferation of murine pluripotent hematopoietic stem cells.

Authors:  J L Spivak; R R Smith; J N Ihle
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808
  8 in total

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