Literature DB >> 6414809

Effect of alkaline glutaraldehyde on hepatitis B virus antigens.

K Adler-Storthz, L M Sehulster, G R Dreesman, F B Hollinger, J L Melnick.   

Abstract

The potential of alkaline 2% glutaraldehyde solutions, with and without surface active agents, to alter the antigenicity of hepatitis B virus (HBV) was analyzed and compared to the antigenic alternation capacities of 0.525% sodium hypochlorite and 2.02% formaldehyde solutions. After treatment of a hepatitis B surface antigen-positive plasma at room temperature for 10 min, there was a 51-67% reduction in surface antigen level and a 90-94% decrease in hepatitis B core antigenicity. Glutaraldehyde is proposed as an alternative to the more noxious hypochlorite and formaldehyde solutions for disinfection of HBV-contaminated articles.

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Year:  1983        PMID： 6414809     DOI： 10.1007/BF02019460

Source DB:  PubMed          Journal:  Eur J Clin Microbiol        ISSN： 0722-2211            Impact factor:   3.267


  26 in total

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Journal:  Zentralbl Bakteriol Mikrobiol Hyg B       Date:  1982-04

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Journal:  J Immunol       Date:  1972-10       Impact factor: 5.422

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Journal:  J Clin Microbiol       Date:  1976-11       Impact factor: 5.948
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  4 in total

1.  Effects of UVA irradiation, aryl azides, and reactive oxygen species on the orthogonal inactivation of the human immunodeficiency virus (HIV-1).

Authors:  Julie M Belanger; Yossef Raviv; Mathias Viard; M Jason de la Cruz; Kunio Nagashima; Robert Blumenthal
Journal:  Virology       Date:  2011-07-02       Impact factor: 3.616

2.  Characterization of the effects of aryl-azido compounds and UVA irradiation on the viral proteins and infectivity of human immunodeficiency virus type 1.

Authors:  Julie M Belanger; Yossef Raviv; Mathias Viard; Michael Jason de la Cruz; Kunio Nagashima; Robert Blumenthal
Journal:  Photochem Photobiol       Date:  2010 Sep-Oct       Impact factor: 3.421

Review 3.  Antiseptics and disinfectants: activity, action, and resistance.

Authors:  G McDonnell; A D Russell
Journal:  Clin Microbiol Rev       Date:  1999-01       Impact factor: 26.132

4.  Canine coronavirus inactivation with physical and chemical agents.

Authors:  Annamaria Pratelli
Journal:  Vet J       Date:  2007-05-21       Impact factor: 2.688
  4 in total

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