Literature DB >> 6414499

High potassium concentration in a parenteral preparation of glyceryl trinitrate. Need for caution if given by intracoronary injection.

S C Webb, R Canepa-Anson, A F Rickards, P A Poole-Wilson.   

Abstract

Glyceryl trinitrate (Tridil) was given by intracoronary injection to a patient who developed coronary artery spasm during angioplasty. Transient exacerbation of chest pain and electrocardiographic changes occurred. This formulation of the drug contains a high concentration of potassium ions and should not be given by this route.

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Year:  1983        PMID: 6414499      PMCID: PMC481429          DOI: 10.1136/hrt.50.4.395

Source DB:  PubMed          Journal:  Br Heart J        ISSN: 0007-0769


  4 in total

1.  Potassium and isolated coronary vascular smooth muscle.

Authors:  J M Norton; R Detar
Journal:  Am J Physiol       Date:  1972-02

Review 2.  Potassium and experimental coronary occlusion.

Authors:  A S Harris
Journal:  Am Heart J       Date:  1966-06       Impact factor: 4.749

3.  Relief by intracoronary glyceryl trinitrate of coronary artery spasm resistant to sublingual route of administration.

Authors:  L G Bentivoglio; A Grüntzig
Journal:  Br Heart J       Date:  1981-11

4.  Action of intracoronary nitroglycerin in refractory coronary artery spasm.

Authors:  C J Pepine; R L Feldman; C R Conti
Journal:  Circulation       Date:  1982-02       Impact factor: 29.690

  4 in total
  2 in total

1.  Continuous recording of coronary sinus oxygen saturation during atrial pacing in patients with coronary artery disease or with syndrome X.

Authors:  T Crake; R Canepa-Anson; L Shapiro; P A Poole-Wilson
Journal:  Br Heart J       Date:  1988-01

2.  Potassium exchange in the human heart during atrial pacing and myocardial ischaemia.

Authors:  S C Webb; P A Poole-Wilson
Journal:  Br Heart J       Date:  1986-06
  2 in total

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