Literature DB >> 6413129

Why do inadvertent pregnancies occur in oral contraceptive users? Effectiveness of oral contraceptive regimens and interfering factors.

I S Fraser, R P Jansen.   

Abstract

Inadvertent pregnancies in combined pill users are not uncommon, and are usually due to errors of tablet taking. However, many factors may contribute to 'pill failure'. In this review the endocrine pharmacology of pill use and the changes reported with missed pills have been considered in detail. The influences of other factors including drug interactions have been reviewed and a series of recommendations made for reducing the risk of pregnancy in each of these circumstances.

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Keywords:  Behavior; Biology; Contraception; Contraception Failure--determinants; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods--contraindications; Contraceptive Methods--determinants; Contraceptive Methods--pharmacodynamics; Contraceptive Mode Of Action; Contraceptive Usage; Demographic Factors; Endocrine System; Family Planning; Hormones; Inhibition Of Fertilization; Oral Contraceptives, Combined; Oral Contraceptives--contraindications; Oral Contraceptives--determinants; Oral Contraceptives--pharmacodynamics; Ovulation Suppression; Physiology; Population; Population Dynamics; Psychological Factors; Reproductive Control Agents; Sperm Transport Inhibition; Time Factors

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Year:  1983        PMID: 6413129     DOI: 10.1016/0010-7824(83)90019-7

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  7 in total

Review 1.  Pharmacokinetic drug interactions between oral contraceptives and second-generation anticonvulsants.

Authors:  K Wilbur; M H Ensom
Journal:  Clin Pharmacokinet       Date:  2000-04       Impact factor: 6.447

2.  Contraceptive choices, pregnancy rates, and outcomes in a microbicide trial.

Authors:  Sengeziwe Sibeko; Cheryl Baxter; Nonhlanhla Yende; Quarraisha Abdool Karim; Salim S Abdool Karim
Journal:  Obstet Gynecol       Date:  2011-10       Impact factor: 7.661

Review 3.  Pharmacokinetic drug interactions with oral contraceptives.

Authors:  D J Back; M L Orme
Journal:  Clin Pharmacokinet       Date:  1990-06       Impact factor: 6.447

Review 4.  Clinical pharmacokinetics of contraceptive steroids. An update.

Authors:  G M Shenfield; J M Griffin
Journal:  Clin Pharmacokinet       Date:  1991-01       Impact factor: 6.447

Review 5.  Long-cycle treatment with oral contraceptives.

Authors:  Inka Wiegratz; Herbert Kuhl
Journal:  Drugs       Date:  2004       Impact factor: 9.546

6.  Should oral contraceptives be available without prescription?

Authors:  J Trussell; F Stewart; M Potts; F Guest; C Ellertson
Journal:  Am J Public Health       Date:  1993-08       Impact factor: 9.308

Review 7.  Oral contraceptives. Are drug interactions of clinical significance?

Authors:  G M Shenfield
Journal:  Drug Saf       Date:  1993-07       Impact factor: 5.606

  7 in total

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