| Literature DB >> 6413084 |
S A Wrighton, J K Pai, G C Mueller.
Abstract
Treatment of bovine lymphocytes with phorbol esters activates an oxygen-dependent system for the formation of a class of arachidonic acid metabolites which appears distinct from prostaglandins, prostacyclins, thromboxanes and leukotrienes. A full activation of the system is achieved within minutes by 10(-7) M 12-O-tetradecanoylphorbol-13-acetate. This activation can be largely prevented by the lipoxygenase inhibitors, 5,8,11,14-eicosatetraynoic acid and nordihydroguaiaretic acid.Entities:
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Year: 1983 PMID： 6413084 DOI： 10.1093/carcin/4.10.1247
Source DB: PubMed Journal: Carcinogenesis ISSN： 0143-3334 Impact factor: 4.944