Literature DB >> 6411732

Monooxygenase activity of human epithelial cells (HeLa): comparison of the response to treatment by arylhydrocarbons and diterpene esters.

W G Pyerin, E Hecker.   

Abstract

Arylhydrocarbons are inducers of monooxygenase activity in epithelial cells in culture (Hela) whereas diterpene esters are not. This is one more example of a specific biochemical difference - here in gene activation - exhibited by tumor initiators and tumor promoters of the classes of compounds assayed.

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Year:  1983        PMID: 6411732     DOI: 10.1007/BF00399901

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.553


  18 in total

1.  Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures.

Authors:  S H Yuspa; U Lichti; T Ben; E Patterson; H Hennings; T J Slaga; N Colburn; W Kelsey
Journal:  Nature       Date:  1976-07-29       Impact factor: 49.962

2.  Tumor initiators and promoters in the induction of Epstein-Barr virus.

Authors:  H zur Hausen; G W Bornkamm; R Schmidt; E Hecker
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

3.  The function and mechanism of promoters of carcinogenesis.

Authors:  R K Boutwell
Journal:  CRC Crit Rev Toxicol       Date:  1974-01

4.  The role of ribonucleic acid and protein synthesis in microsomal aryl hydrocarbon hydroxylase induction in cell culture. The independence of transcription and translation.

Authors:  D W Nebert; H V Gelboin
Journal:  J Biol Chem       Date:  1970-01-10       Impact factor: 5.157

5.  The effects of dexamethasone on mouse skin initiation and aryl hydrocarbon hydroxylase.

Authors:  S Thompson; T J Slaga
Journal:  Eur J Cancer       Date:  1976-05       Impact factor: 9.162

6.  Inflammatory, tumor initiating and promoting activities of polycyclic aromatic hydrocarbons and diterpene esters in mouse skin as compared with their prostaglandin releasing potency in vitro.

Authors:  K Brune; H Kalin; R Schmidt; E Hecker
Journal:  Cancer Lett       Date:  1978-06       Impact factor: 8.679

7.  Induction of mouse epidermal ornithine decarboxylase activity and skin tumors by 7,12-dimethylben.

Authors:  A K Verma; E A Conrad; R K Boutwell
Journal:  Carcinogenesis       Date:  1980-07       Impact factor: 4.944

8.  Tumor initiation by 7,12-dimethylbenz[a]anthracene in dermal melanocytes of hamster: inhibition through 7,8-benzoflavone.

Authors:  K Goerttler; H Loehrke; B Hesse; W G Pyerin
Journal:  Carcinogenesis       Date:  1982       Impact factor: 4.944

9.  Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.

Authors:  T G O'Brien; R C Simsiman; R K Boutwell
Journal:  Cancer Res       Date:  1975-07       Impact factor: 12.701

10.  Skin tumor promotion by phorbol esters is a two-stage process.

Authors:  G Fürstenberger; D L Berry; B Sorg; F Marks
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

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  1 in total

1.  Posttranslational modifications of the cytochrome P-450 monooxygenase system.

Authors:  W Pyerin; F Horn; H Taniguchi
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553

  1 in total

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