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Literature DB >> 6411486

Positive inotropic and chronotropic effect of alloimmune sera on isolated mouse atria.

G A Cremaschi, A M Genaro, M E Sales, L Sterin-Borda.

Abstract

The effects of alloimmune sera on the contractile tension and frequency of spontaneously beating isolated mouse atria were explored. Immune sera enhanced frequency as well as tension; both effects were blocked by the presence of propranolol. In contrast, pretreatment with 6-OH dopamine potentiated the stimulatory action of immune sera.

Entities: Chemical Species

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Year: 1983 PMID： 6411486 DOI： 10.1007/BF01989785

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

12 in total

1. [Immunologic aspects of murine allogeneic tumor growth (author's transl)].

Authors: M Braun; F Saal; C D Pasqualini
Journal: Sangre (Barc) Date: 1974

Review 2. Experimental cardiac anaphylaxis. Physiologic, pharmacologic and biochemical aspects of immune reactions in the isolated heart.

Authors: G A Feigen; D J Prager
Journal: Am J Cardiol Date: 1969-10 Impact factor: 2.778

3. Inotropic effect of PGE1 and PGE2 on isolated rat atria. Influence of adrenergic mechanisms.

Authors: L Sterin-Borda; L Canga; A Pissani; A L Gimeno
Journal: Prostaglandins Date: 1980-11

4. Correlation of norepinephrine content with observations of adrenergic nerves after a single dose of 6-hydroxydopamine in the rat.

Authors: H Goldman; D Jacobowitz
Journal: J Pharmacol Exp Ther Date: 1971-01 Impact factor: 4.030

5. "Antibodies raised against beta-adrenergic receptors stimulate adenylate cyclase".

Authors: P O Couraud; C Delavier-Klutchko; O Durieu-Trautmann; A D Strosberg
Journal: Biochem Biophys Res Commun Date: 1981-04-30 Impact factor: 3.575

6. Frequency-force relationship on isolated rat and guinea pig atria. Effects of cholinergic and adrenergic receptor antagonists.

Authors: L S de Borda; A L Gimeno; M F Gimeno
Journal: Proc Soc Exp Biol Med Date: 1974-04

7. Altered inotropic and chronotropic effects of noradrenaline on isolated rat atria exposed to chagasic sera. Influences of cocaine, normetanephrine and U-0521 (3'-4'-dihydroxy-2-methyl propiophenone.

Authors: A L Gimeno; M F Gimeno; L Sterin-Borda; P M Cossio; N Sterin-Speziale; C Diez; S M Seara; R M Arana
Journal: Cardiovasc Res Date: 1979-12 Impact factor: 10.787

Positive inotropic and chronotropic effect of alloimmune sera on isolated mouse atria.

1. [Immunologic aspects of murine allogeneic tumor growth (author's transl)].

Review 2. Experimental cardiac anaphylaxis. Physiologic, pharmacologic and biochemical aspects of immune reactions in the isolated heart.

3. Inotropic effect of PGE1 and PGE2 on isolated rat atria. Influence of adrenergic mechanisms.

4. Correlation of norepinephrine content with observations of adrenergic nerves after a single dose of 6-hydroxydopamine in the rat.

5. "Antibodies raised against beta-adrenergic receptors stimulate adenylate cyclase".

6. Frequency-force relationship on isolated rat and guinea pig atria. Effects of cholinergic and adrenergic receptor antagonists.

7. Altered inotropic and chronotropic effects of noradrenaline on isolated rat atria exposed to chagasic sera. Influences of cocaine, normetanephrine and U-0521 (3'-4'-dihydroxy-2-methyl propiophenone.

8. beta-Adrenergic effect of antibodies from chagasic patients and normal human lymphocytes on isolated rat atria.

9. Chagasic sera alter the effects of ouabain on isolated rat atria. Participation of adrenergic mechanisms.

10. Calcium ions and the influence of chagasic sera on the effects of ouabain on isolated rat atria.

1. Alloimmune IgG binds and modulates cardiac beta-adrenoceptor activity.