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Literature DB >> 6411172

Changes in volume and density of platelets in myocardial infarction.

J F Martin, J Plumb, R S Kilbey, Y T Kishk.

Abstract

The distributions of platelet volume and density were measured in 15 men suffering myocardial infarction and in 22 healthy controls. The method used separated 93% of the total platelet population from whole blood. Mean platelet volume of the study group compared with that of controls was increased by a mean of 0.98 fl (p less than 0.001) in the first 12 hours after myocardial infarction, and by 1.24 fl six weeks later (p less than 0.001). Distribution of platelet volume remained log normal after myocardial infarction. Modal platelet density was increased by a mean of 25 g/l (p less than 0.05) after myocardial infarction. Platelet volume is probably chronically large in men suffering myocardial infarction and may be related to changes in megakaryocytes. It is suggested that the increase in platelet volume occurs before infarction.

Entities: Disease Species

Mesh：

Year: 1983 PMID： 6411172 PMCID： PMC1548755 DOI： 10.1136/bmj.287.6390.456

Source DB: PubMed Journal: Br Med J (Clin Res Ed) ISSN： 0267-0623

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1. Mean platelet volume in acute coronary syndrome.

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4. Mean platelet volume: ready for prime time?

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Authors: Zora Sušilović Grabovac; Darija Baković; Mislav Lozo; Irena Pintarić; Željko Dujić
Journal: Int J Angiol Date: 2017-10-04

6. Do immature platelet levels in chest pain patients presenting to the emergency department aid in the diagnosis of acute coronary syndrome?

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