Literature DB >> 6410695

Intoxication with sodium valproate. A case report.

R L Karlsen, K Kett, O Henriksen.   

Abstract

Sodium valproate is a relatively new compound in the treatment of epilepsy. A female patient was admitted to the hospital after voluntary intake of 30 g sodium valproate. Her serum concentration was 4925 mumol/l, but the course of the intoxication was mild and the patient was soporous for only 12 hours after intake of the compound. Biochemical data may suggest a slight transitory liver affection.

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Year:  1983        PMID: 6410695     DOI: 10.1111/j.0954-6820.1983.tb03759.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  5 in total

1.  Acute sodium valproate intoxication: occurrence of renal failure and treatment with haemoperfusion-haemodialysis.

Authors:  A M Roodhooft; K Van Dam; D Haentjens; G A Verpooten; K J Van Acker
Journal:  Eur J Pediatr       Date:  1990-02       Impact factor: 3.183

2.  Acute valproic acid overdose. Clinical course and pharmacokinetic disposition of valproic acid and metabolites.

Authors:  R E Dupuis; S N Lichtman; G M Pollack
Journal:  Drug Saf       Date:  1990 Jan-Feb       Impact factor: 5.606

3.  Survival after severe self poisoning with sodium valproate.

Authors:  M Lakhani; M E McMurdo
Journal:  Postgrad Med J       Date:  1986-05       Impact factor: 2.401

4.  A case of valproate intoxication with excessive brain edema.

Authors:  G Hintze; H H Klein; H Prange; H Kreuzer
Journal:  Klin Wochenschr       Date:  1987-05-04

Review 5.  Valproate-associated hepatotoxicity and its biochemical mechanisms.

Authors:  M J Eadie; W D Hooper; R G Dickinson
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Mar-Apr
  5 in total

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