Literature DB >> 6409459

Testicular damage after radioactive iodine (I-131) therapy for thyroid cancer.

D J Handelsman, J R Turtle.   

Abstract

Testicular damage was evaluated in twelve men by determination of sperm counts, serum FSH, LH, and testosterone up to 3 1/2 years after treatment with radioactive iodine (131I) therapy for thyroid cancer. Dose-dependent spermatogenic damage with elevation of serum FSH was evident. Full recovery in one and partial recovery in another patient was documented during 2 1/2 years of follow-up. Serial study in two patients documented a small but significant effect of 50 mCi 131I on serum FSH levels and clinically important effects appear to be restricted to men having multiple doses totalling over 100 mCi.

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Year:  1983        PMID: 6409459     DOI: 10.1111/j.1365-2265.1983.tb02876.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN: 0300-0664            Impact factor:   3.478


  10 in total

1.  Radioiodine for hyperthyroidism.

Authors:  D O'Halloran; S M Shalet
Journal:  BMJ       Date:  1992-11-07

2.  The value of intraoperative scintigraphy as a routine procedure in thyroid carcinoma.

Authors:  S Lennquist; J Persliden; S Smeds
Journal:  World J Surg       Date:  1988-10       Impact factor: 3.352

3.  Intraoperative scintigraphy in surgical treatment of thyroid carcinoma: evaluation of a new technique.

Authors:  S Lennquist; J Persliden; S Smeds
Journal:  World J Surg       Date:  1986-08       Impact factor: 3.352

Review 4.  Thyroid disease and male reproductive function.

Authors:  G E Krassas; P Perros
Journal:  J Endocrinol Invest       Date:  2003-04       Impact factor: 4.256

5.  Pregnancy after high therapeutic doses of iodine-131 in differentiated thyroid cancer: potential risks and recommendations.

Authors:  D Casara; D Rubello; G Saladini; A Piotto; M R Pelizzo; M E Girelli; B Busnardo
Journal:  Eur J Nucl Med       Date:  1993-03

6.  Iodine 131 thyroid ablation in female children and adolescents: long-term risk of infertility and birth defects.

Authors:  M B Smith; H Xue; H Takahashi; A Cangir; R J Andrassy
Journal:  Ann Surg Oncol       Date:  1994-03       Impact factor: 5.344

7.  Gonadal damage due to radioactive iodine (I131) treatment for thyroid carcinoma.

Authors:  S R Ahmed; S M Shalet
Journal:  Postgrad Med J       Date:  1985-04       Impact factor: 2.401

Review 8.  FDA-approved medications that impair human spermatogenesis.

Authors:  Jiayi Ding; Xuejun Shang; Zhanhu Zhang; Hua Jing; Jun Shao; Qianqian Fei; Elizabeth R Rayburn; Haibo Li
Journal:  Oncotarget       Date:  2017-02-07

9.  Effects of therapy with [177Lu-DOTA 0,Tyr 3]octreotate on endocrine function.

Authors:  Jaap J M Teunissen; Eric P Krenning; Frank H de Jong; Yolanda B de Rijke; Richard A Feelders; Maarten O van Aken; Wouter W de Herder; Dik J Kwekkeboom
Journal:  Eur J Nucl Med Mol Imaging       Date:  2009-05-27       Impact factor: 9.236

10.  Sperm DNA fragmentation after radioiodine treatment for differentiated thyroid cancer.

Authors:  Camille Esquerré-Lamare; François Isus; Nathalie Moinard; Louis Bujan
Journal:  Basic Clin Androl       Date:  2015-08-02
  10 in total

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