Literature DB >> 6409361

[Somatocrinin induces growth hormone release in a case of growth hormone deficiency of hypothalamic origin in a child].

G Sassolas, H Rousset, R Cohen, P Chatelain, B Claustrat, S Laporte, B Laferrère, A El Charfi, S Ferry.   

Abstract

Somatocrinin (hp-GRF-44), a growth hormone releasing factor, stimulates acute pituitary response in a 11 years and 4 months old boy, with growth hormone deficiency. The capability of the anterior pituitary to secrete growth hormone in response to an IV injection of somatocrinin (120 micrograms 4 micrograms/kg) was documented, therefore proving the hypothalamic origin of the deficit which had been suspected because of association of diabetes insipidus and hyperprolactinemia.

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Year:  1983        PMID: 6409361

Source DB:  PubMed          Journal:  C R Seances Acad Sci III        ISSN: 0249-6313


  2 in total

1.  Exogenous growth hormone inhibits growth hormone-releasing factor-induced growth hormone secretion in normal men.

Authors:  S M Rosenthal; J A Hulse; S L Kaplan; M M Grumbach
Journal:  J Clin Invest       Date:  1986-01       Impact factor: 14.808

2.  Growth hormone releasing factor: comparison of two analogues and demonstration of hypothalamic defect in growth hormone release after radiotherapy.

Authors:  A Grossman; N Lytras; M O Savage; J A Wass; D H Coy; L H Rees; A E Jones; G M Besser
Journal:  Br Med J (Clin Res Ed)       Date:  1984-06-16
  2 in total

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