Literature DB >> 640874

[Studies on the genetics of otosclerosis (author's transl)].

M Schröder, U Langenbeck.   

Abstract

101 families with confirmed otosclerosis were investigated, and after correction for age an incidence was found of otosclerosis of 29.5% amongst the parents, 17.9% amongst the siblings and 8.8% amongst offspring. The statistical data for otosclerosis published to date were treated similarly giving together with our own as large a collection as possible. From this the risk of repeat occurrence of otosclerosis could be calculated to 10% in the brothers and 20% in the sisters of otosclerotic patients. The risk rates of occurrence for their children are the same. These data are intended for use in the genetic counseling of this disorder.

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Year:  1978        PMID: 640874

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  1 in total

1.  Genetic analysis for early diagnosis of otorhinolaryngeal diseases.

Authors:  Peter Propping
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2010-10-07
  1 in total

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