| Literature DB >> 6407226 |
A M Rodriguez, D Afchain, F Santoro, H Bazin, A Capron.
Abstract
The role of the thymus on immunity of rats against Trypanosoma cruzi infection was investigated in vivo. The athymic (nu/nu) rats were shown to be significantly more susceptible to the acute phase of the infection than the control nu/+ rats, as measured by increased parasitemia and mortality. Specific anti-T. cruzi antibodies, complement, IgM and IgG2a serum levels were determined. The results would indicate the essential role of antibodies in immunity to acute Chagas' disease through T-dependent immune response.Entities:
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Year: 1983 PMID： 6407226 DOI： 10.1007/BF00926950
Source DB: PubMed Journal: Z Parasitenkd ISSN： 0044-3255