| Literature DB >> 6407187 |
J J van den Oord, K Geboes, C de Wolf-Peeters, V J Desmet.
Abstract
Gallbladders of 12 cases with chronic cholecystitis showing pseudopyloric glands (PPG) and of 18 cases with acute cholecystitis or chronic cholecystitis but without PPG were examined by the peroxidase - antiperoxidase (PAP) method using rabbit antibody against human lysozyme (LM). LM-immunoreactivity was detected in the cytoplasm of PPG and, to a lesser extent, in the pits of epithelial crypts that gave rise to PPG. No LM was found in normal gallbladders; in cases of cholecystitis without PPG, LM-immunoreactivity was restricted to infiltrating inflammatory cells. The presence of LM in PPG suggests that PPG represent functional metaplastic areas, involved in the non-specific defence mechanisms through participation of LM.Entities:
Mesh：
Substances：
Year: 1983 PMID： 6407187 DOI： 10.1007/BF00612949
Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398