Literature DB >> 6407157

Cell surface glycoproteins of Trypanosoma cruzi: protective immunity in mice and antibody levels in human chagasic sera.

D Snary.   

Abstract

Two cell surface glycoproteins from Trypanosoma cruzi have been compared for their ability to protect mice against an acute lethal infection. One of these, a 90,000 glycoprotein found on all stages of the parasite, protected against both bloodstream and metacyclic trypomastigote challenge. A 72,000 glycoprotein found only on insect-derived stages of T. cruzi protected only against a metacyclic trypomastigote challenge. Antibody against both of these glycoproteins was present in human chagasic sera.

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Year:  1983        PMID: 6407157     DOI: 10.1016/0035-9203(83)90037-8

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  8 in total

1.  Trypanosoma cruzi glycoprotein 72: immunological analysis and cellular localization.

Authors:  G Harth; A A Mills; T Souto-Padrón; W de Souza
Journal:  Mol Cell Biochem       Date:  1992-01-15       Impact factor: 3.396

2.  Prevalence of antibodies to 72-kilodalton glycoprotein (GP72) in patients with Chagas' disease and further evidence of zymodeme-associated expression of GP72 carbohydrate epitopes.

Authors:  M Schechter; A F Stevens; A O Luquetti; D Snary; A K Allen; M A Miles
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

Review 3.  Carbohydrate immunity in American trypanosomiasis.

Authors:  L R Travassos; I C Almeida
Journal:  Springer Semin Immunopathol       Date:  1993

4.  Studies on the structure of a phosphoglycoprotein from the parasitic protozoan Trypanosoma cruzi.

Authors:  M A Ferguson; A K Allen; D Snary
Journal:  Biochem J       Date:  1983-08-01       Impact factor: 3.857

5.  Cruzipain induces both mucosal and systemic protection against Trypanosoma cruzi in mice.

Authors:  Anita R Schnapp; Chris S Eickhoff; Donata Sizemore; Roy Curtiss; Daniel F Hoft
Journal:  Infect Immun       Date:  2002-09       Impact factor: 3.441

6.  Differences in resistance to reinfection with low and high inocula of Trypanosoma cruzi in chagasic mice treated with nifurtimox and relation to immune response.

Authors:  P Cabeza Meckert; J G Chambó; R P Laguens
Journal:  Antimicrob Agents Chemother       Date:  1988-02       Impact factor: 5.191

Review 7.  Experimental Vaccines against Chagas Disease: A Journey through History.

Authors:  Olivia Rodríguez-Morales; Víctor Monteón-Padilla; Silvia C Carrillo-Sánchez; Martha Rios-Castro; Mariana Martínez-Cruz; Alejandro Carabarin-Lima; Minerva Arce-Fonseca
Journal:  J Immunol Res       Date:  2015-05-18       Impact factor: 4.818

8.  gp72, the 72 kilodalton glycoprotein, is the membrane acceptor site for C3 on Trypanosoma cruzi epimastigotes.

Authors:  K Joiner; S Hieny; L V Kirchhoff; A Sher
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307

  8 in total

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