Literature DB >> 6407112

Gamma interferon synthesis by human thymocytes and T lymphocytes inhibited by cyclosporin A.

G H Reem, L A Cook, J Vilcek.   

Abstract

Cyclosporin A depresses the synthesis of gamma interferon by human thymocytes and T lymphocytes in vitro. This observation is of potential clinical significance because the long-term treatment of transplant patients with cyclosporin A, a widely used immunosuppressive agent, can give rise to B-cell lymphoma resulting from Epstein-Barr virus activation.

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Year:  1983        PMID： 6407112     DOI： 10.1126/science.6407112

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  38 in total

1.  Cyclosporin A inhibits phorbol ester-induced activation of superoxide production in resident mouse peritoneal macrophages.

Authors:  M D Chiara; F Bedoya; F Sobrino
Journal:  Biochem J       Date:  1989-11-15       Impact factor: 3.857

2.  T-cell-independent macrophage activation in mice induced with rRNA from Listeria monocytogenes and dimethyldioctadecylammonium bromide.

Authors:  J F van den Bosch; I Y Kanis; A C Antonissen; W A Buurman; C P van Boven
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

Review 3.  The use of therapeutic drug monitoring to optimise immunosuppressive therapy.

Authors:  S M Tsunoda; F T Aweeka
Journal:  Clin Pharmacokinet       Date:  1996-02       Impact factor: 6.447

Review 4.  Corticosteroid sparing agents in asthma.

Authors:  J M Hill; A E Tattersfield
Journal:  Thorax       Date:  1995-05       Impact factor: 9.139

Review 5.  Cardiac transplantation. Selection, immunosuppression, and survival.

Authors:  L W Stevenson; H Laks; P I Terasaki; B D Kahan; D C Drinkwater
Journal:  West J Med       Date:  1988-11

6.  Cyclosporin A prevents induction of the interleukin 2 receptor gene in cultured murine thymocytes.

Authors:  J F Gauchat; E W Khandjian; R Weil
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

7.  Differential effect of cyclosporin A on activation signaling in human T cell lines.

Authors:  B Manger; K J Hardy; A Weiss; J D Stobo
Journal:  J Clin Invest       Date:  1986-05       Impact factor: 14.808

8.  Complexity of the primary genetic response to mitogenic activation of human T cells.

Authors:  P F Zipfel; S G Irving; K Kelly; U Siebenlist
Journal:  Mol Cell Biol       Date:  1989-03       Impact factor: 4.272

9.  In vitro and in vivo action of cyclosporin A on the induction of human interleukin-2 receptor alpha and beta chains.

Authors:  S Caillat-Zucman; L Chatenoud; J F Bach
Journal:  Clin Exp Immunol       Date:  1989-08       Impact factor: 4.330

10.  Rat pancreatic islet pretreatment with anti-MHC class II monoclonal antibodies and culture: in vitro MLIC test response does not predict islet allograft survival.

Authors:  R G Bretzel; B K Flesch; G Brennenstuhl; I Greiner; B J Hering; M Woehrle; K Federlin
Journal:  Acta Diabetol       Date:  1993       Impact factor: 4.280
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