| Literature DB >> 6406439 |
J Mendels, M M Amin, G Chouinard, A J Cooper, J E Miles, R A Remick, B Saxena, S K Secunda, A N Singh.
Abstract
A double-blind controlled trial comparing a standard antidepressant drug, amitriptyline, with a new compound, bupropion, was conducted at six centers. There was a placebo washout, after which patients were assigned in a randomized fashion to one of the two treatments. No significant difference was found in therapeutic response to the two drugs after 4 weeks of treatment. Anticholinergic and cardiovascular side effects were less common in the bupropion-treated patients.Entities:
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Year: 1983 PMID： 6406439
Source DB: PubMed Journal: J Clin Psychiatry ISSN： 0160-6689 Impact factor: 4.384