| Literature DB >> 6405797 |
Abstract
It was found that aldolase activity declined considerably in the lens of adult animals with increasing age. Immunoassay showed that defective aldolase C molecules were accumulated. In addition, antibody prepared against denatured enzyme preferentially removes inactive molecules from lens homogenates without affecting active molecules. It is concluded that defective aldolase molecules encountered in aging lenses are at least partially denatured and are inactive.Entities:
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Year: 1983 PMID： 6405797 DOI： 10.1016/0304-4165(83)90104-6
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002