Biliary calculi in chronic Salmonella carriers and healthy controls: a controlled study.

A controlled study was performed to evaluate the incidence of gall bladder and biliary duct disease in chronic typhoid and paratyphoid carriers. Eight chronic carriers were compared with a comparable group of control persons who had previously had acute typhoid or paratyphoid fever without developing a chronic carrier state. By combined surgical and radiological evaluation biliary calculi were detected in 88% of the carrier group and in 11% in the control group. This difference is statistically significant (p less than 0.02). No difference in biliary function was found between the two groups.