Literature DB >> 6405069

Cell lines derived from human ovarian carcinomas: growth stimulation by gonadotropic and steroid hormones.

W E Simon, M Albrecht, M Hänsel, M Dietel, F Hölzel.   

Abstract

Carcinoma cell lines established from 5 patients with advanced tumors of ovarian location were characterized by karyotypes and growth properties in serum-free medium. In early passages of the cultivation, the growth of cell lines derived from tumors of fairly differentiated histology was stimulated by human follicle-stimulating hormone or human chorionic gonadotropin-human luteinizing hormone. Cells obtained from poorly differentiated carcinomas were unresponsive to gonadotropins. The proliferation of cell lines derived from a malignant clear cell carcinoma and from the ovarian metastasis of an advanced mammary carcinoma was enhanced by cortisol. The results imply that hormonal factors in concentrations physiologically occurring in human serum may support the in vivo growth of ovarian tumors.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6405069

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  21 in total

Review 1.  Epithelial ovarian cancer experimental models.

Authors:  E Lengyel; J E Burdette; H A Kenny; D Matei; J Pilrose; P Haluska; K P Nephew; D B Hales; M S Stack
Journal:  Oncogene       Date:  2013-08-12       Impact factor: 9.867

Review 2.  Clinical applications of hormonal therapy in ovarian cancer.

Authors:  Gautam G Rao; David S Miller
Journal:  Curr Treat Options Oncol       Date:  2005-03

3.  Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells.

Authors:  Young-Han Park; Su Jin Kim; Byung-Hoon Jeong; Thomas J Herzog; Jason Wright; Jan Kitajewski; Chae Chun Rhim; Pong Rheem Jang; Jung Bae Kang; Sung Ju Kim
Journal:  J Gynecol Oncol       Date:  2010-06-30       Impact factor: 4.401

Review 4.  Oral contraceptives and cancer. A review of the evidence.

Authors:  C La Vecchia; A Tavani; S Franceschi; F Parazzini
Journal:  Drug Saf       Date:  1996-04       Impact factor: 5.606

5.  Alteration of steroid hormone sensitivity during the cultivation of human mammary carcinoma cells.

Authors:  W E Simon; M Hänsel; M Dietel; L Matthiesen; M Albrecht; F Hölzel
Journal:  In Vitro       Date:  1984-03

6.  Establishment of primary cell cultures: experiences with 155 cell strains.

Authors:  M Dietel; H Arps; D Gerding; M Trapp; A Niendorf
Journal:  Klin Wochenschr       Date:  1987-06-01

7.  Production of insulin-like growth factor binding proteins by human ovarian carcinoma cells.

Authors:  J Hofmann; B Wegmann; R Hackenberg; R Kunzmann; K D Schulz; K Havemann
Journal:  J Cancer Res Clin Oncol       Date:  1994       Impact factor: 4.553

8.  Effectiveness of antineoplastic drugs on the proliferation of human mammary and ovarian carcinoma cells in monolayer culture.

Authors:  F Hölzel; M Albrecht; W E Simon; M Hänsel; R Metz; J Schweizer; M Dietel
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553

9.  Individual chemosensitivity of in vitro proliferating mammary and ovarian carcinoma cells in comparison to clinical results of chemotherapy.

Authors:  M Albrecht; W E Simon; F Hölzel
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553

10.  Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormone.

Authors:  T Yano; J Pinski; S Radulovic; A V Schally
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.