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Literature DB >> 6404836

Do lymphocytes from Chagasic patients respond to heart antigens?

Abstract

Lymphocyte transformation studies of nonadherent lymphocytes from chronic Chagasic and uninfected persons demonstrated that responses of all individuals to a mouse heart homogenate showed a correlation with responses to streptococcal antigens. Considering the known cross-reactions between streptococcal and cardiac antigens and the high reactivity of Chagasic patients to streptococcal antigens, it is possible that positive lymphocyte transformation to unfractionated heart antigen preparations may not represent specific reactivity to heart antigens.

Entities: Species

Mesh：

Substances：
Antigens

Year: 1983 PMID： 6404836 PMCID： PMC264931 DOI： 10.1128/iai.40.2.832-835.1983

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

14 in total

Review 1. American trypanosomiasis: Chagas' disease.

Authors: C A Santos-Buch
Journal: Int Rev Exp Pathol Date: 1979

2. Chagasic cardiopathy. Demonstration of a serum gamma globulin factor which reacts with endocardium and vascular structures.

Authors: P M Cossio; C Diez; A Szarfman; E Kreutzer; B Candiolo; R M Arana
Journal: Circulation Date: 1974-01 Impact factor: 29.690

3. Delayed hypersensitivity to heart antigens in Chagas' disease as measured by in vitro lymphocyte stimulation.

Authors: W Mosca; J Plaja
Journal: J Clin Microbiol Date: 1981-07 Impact factor: 5.948

4. Cellular immunity in chronic Chagas' disease.

Authors: O M Montufar; C C Musatti; E Mendes; N F Mendes
Journal: J Clin Microbiol Date: 1977-04 Impact factor: 5.948

5. Microplate enzyme-linked immunosorbent assay for chagas' disease.

Authors: A Voller; C Draper; D E Bidwell; A Bartlett
Journal: Lancet Date: 1975-02-22 Impact factor: 79.321

6. Post-nephrectomy arteriovenous fistula.

Authors: A G Goldstein; D A Delaurentis; A J Schwartz
Journal: J Urol Date: 1967-07 Impact factor: 7.450

7. The immunology of experimental Chagas' disease. IV. Production of lesions in rabbits similar to those of chronic Chagas' disease in man.

Authors: A R Teixeira; M L Teixeira; C A Santos-Buch
Journal: Am J Pathol Date: 1975-07 Impact factor: 4.307

8. Immune response in human Chagas disease II. Lymphocyte blastogenesis in patients with chagasic cardiomyopathy.

Authors: W Mosca
Journal: Acta Cient Venez Date: 1980

9. The immunology of experimental Chagas' disease. 3. Rejection of allogeneic heart cells in vitro.

Authors: C A Santos-Buch; A R Teixeira
Journal: J Exp Med Date: 1974-07-01 Impact factor: 14.307

10. IMMUNOLOGIC RELATION OF STREPTOCOCCAL AND TISSUE ANTIGENS. III. PRESENCE IN HUMAN SERA OF STREPTOCOCCAL ANTIBODY CROSS-REACTIVE WITH HEART TISSUE. ASSOCIATION WITH STREPTOCOCCAL INFECTION, RHEUMATIC FEVER, AND GLOMERULONEPHRITIS.

Authors: M H KAPLAN; K H SVEC
Journal: J Exp Med Date: 1964-04-01 Impact factor: 14.307

4 in total