| Literature DB >> 6403986 |
M R Urist, R J DeLange, G A Finerman.
Abstract
Bone morphogenetic protein and bone-derived growth factors are biochemical tools for research on induced cell differentiation and local mechanisms controlling cell proliferation. Bone morphogenetic protein irreversibly induces differentiation of perivascular mesenchymal-type cells into osteoprogenitor cells. Bone-derived growth factors are secreted by and for osteoprogenitor cells and stimulate DNA synthesis. Bone generation and regeneration are attributable to the co-efficiency of bone morphogenetic protein and bone-derived growth factors.Mesh:
Substances:
Year: 1983 PMID: 6403986 DOI: 10.1126/science.6403986
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728