| Literature DB >> 6403872 |
Abstract
The three-dimensional chromosome topography in an intact nucleus has been determined using fluorescently stained Drosophila polytene chromosomes, optical fluorescence microscopy and newly developed, generally applicable, cellular image reconstruction techniques. The folding pattern is a complex mixture of parallel chromosomal segments and intertwined coils and shows extensive interaction of the chromosomes with the nuclear envelope.Entities:
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Year: 1983 PMID: 6403872 DOI: 10.1038/302676a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962