Literature DB >> 6403508

Locus of the Pseudomonas aeruginosa toxin A gene.

L F Hanne, T R Howe, B H Iglewski.   

Abstract

The gene for Pseudomonas aeruginosa toxin A has been mapped in the late region of the chromosome of strain PAO. Strain PAO-PR1, which produces parental levels of toxin A antigen that is enzymatically inactive and nontoxic, was used as the donor for R68.45 plasmid-mediated genetic exchange. Strain PAO-PR1 (toxA1) was mated with toxin A-producing strains, and exconjugates for selected prototrophic markers were tested for the transfer of toxA1. The toxA1 gene was located between cnu-9001 and pur-67 at approximately 85 min on the PAO chromosome.

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Year:  1983        PMID： 6403508      PMCID： PMC217470          DOI： 10.1128/jb.154.1.383-386.1983

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.476


  30 in total

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Authors:  T Uchida; A M Pappenheimer; R Greany
Journal:  J Biol Chem       Date:  1973-06-10       Impact factor: 5.157

2.  The roles of various fractions of Pseudomonas aeruginosa in its pathogenesis. 3. Identity of the lethal toxins produced in vitro and in vivo.

Authors:  P V Liu
Journal:  J Infect Dis       Date:  1966-10       Impact factor: 5.226

3.  Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans.

Authors:  D G Evans; R P Silver; D J Evans; D G Chase; S L Gorbach
Journal:  Infect Immun       Date:  1975-09       Impact factor: 3.441

Review 4.  Research in cystic fibrosis (third of three parts).

Authors:  P A di Sant'Agnese; P B Davis
Journal:  N Engl J Med       Date:  1976-09-09       Impact factor: 91.245

5.  A mutant sex factor of Pseudomonas aeruginosa.

Authors:  V A Stanisich; B W Holloway
Journal:  Genet Res       Date:  1972-02       Impact factor: 1.588

6.  Mutation in the structural gene for diphtheria toxin carried by temperate phage .

Authors:  T Uchida; D M Gill; A M Pappenheimer
Journal:  Nat New Biol       Date:  1971-09-01

7.  Neutralizing antibody to Pseudomonas aeruginosa exotoxin in human sera: evidence for in vivo toxin production during infection.

Authors:  M Pollack; L T Callahan; N S Taylor
Journal:  Infect Immun       Date:  1976-10       Impact factor: 3.441

8.  Structure-activity relationships of an exotoxin of Pseudomonas aeruginosa.

Authors:  M L Vasil; D Kabat; B H Iglewski
Journal:  Infect Immun       Date:  1977-04       Impact factor: 3.441

9.  Exotoxin production by clinical isolates of pseudomonas aeruginosa.

Authors:  M Pollack; N S Taylor; L T Callahan
Journal:  Infect Immun       Date:  1977-03       Impact factor: 3.441

10.  Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo.

Authors:  B H Iglewski; P V Liu; D Kabat
Journal:  Infect Immun       Date:  1977-01       Impact factor: 3.441
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  15 in total

1.  Mapping of mutations in Pseudomonas aeruginosa defective in pyoverdin production.

Authors:  R Ankenbauer; L F Hanne; C D Cox
Journal:  J Bacteriol       Date:  1986-07       Impact factor: 3.490

2.  Evidence indicating that the cholera toxin structural genes of Vibrio cholerae RJ1 and 3083-2 are between met and trp.

Authors:  D W Saunders; G J Kubala; A B Vaidya; M G Bramucci
Journal:  Infect Immun       Date:  1983-10       Impact factor: 3.441

3.  Genetic mapping and characterization of Pseudomonas aeruginosa mutants defective in the formation of extracellular proteins.

Authors:  B Wretlind; O R Pavlovskis
Journal:  J Bacteriol       Date:  1984-06       Impact factor: 3.490

4.  Isolation and characterization of alkaline protease-deficient mutants of Pseudomonas aeruginosa in vitro and in a mouse eye model.

Authors:  T R Howe; B H Iglewski
Journal:  Infect Immun       Date:  1984-03       Impact factor: 3.441

5.  Isolation and characterization of Pseudomonas aeruginosa mutants deficient in the utilization of the terpenoid citronellic acid.

Authors:  M L Hector; M F Murphy-Waldorf; T B Giertych; M J Hickey; A A Haggard
Journal:  World J Microbiol Biotechnol       Date:  1993-09       Impact factor: 3.312

6.  Physical mapping of virulence-associated genes in Pseudomonas aeruginosa by transverse alternating-field electrophoresis.

Authors:  V D Shortridge; M L Pato; A I Vasil; M L Vasil
Journal:  Infect Immun       Date:  1991-10       Impact factor: 3.441

7.  Cloning of a gene involved in regulation of exotoxin A expression in Pseudomonas aeruginosa.

Authors:  R C Hedstrom; C R Funk; J B Kaper; O R Pavlovskis; D R Galloway
Journal:  Infect Immun       Date:  1986-01       Impact factor: 3.609

8.  Development of a defined medium and two-step culturing method for improved exotoxin A yields from Pseudomonas aeruginosa.

Authors:  I I Blumentals; R M Kelly; M Gorziglia; J B Kaufman; J Shiloach
Journal:  Appl Environ Microbiol       Date:  1987-09       Impact factor: 5.005

9.  Determination of the amino acid change responsible for the nontoxic, cross-reactive exotoxin A protein (CRM 66) of Pseudomonas aeruginosa PAO-PR1.

Authors:  M J Wick; B H Iglewski
Journal:  J Bacteriol       Date:  1988-11       Impact factor: 3.476

10.  Effect of iron on accumulation of exotoxin A-specific mRNA in Pseudomonas aeruginosa.

Authors:  S Lory
Journal:  J Bacteriol       Date:  1986-12       Impact factor: 3.476
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