Literature DB >> 6402087

Positron emission tomography in venous ulceration and liposclerosis: study of regional tissue function.

N F Hopkins, T J Spinks, C G Rhodes, A S Ranicar, C W Jamieson.   

Abstract

Oxygen-15 administered by continuous inhalation and emission computed tomography were used to study regional tissue oxygen utilisation and blood flow in the limbs of 11 patients with venous ulceration and five patients with liposclerosis due to venous insufficiency. The results showed increased blood flow and appreciably reduced fractional oxygen extraction in the diseased tissues. These findings indicated a local, functional shunting of blood through the abnormal microcirculation of the skin and subcutaneous tissues. This may be an important factor in the aetiology of the skin changes seen in patients with calf muscle pump failure.

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Year:  1983        PMID： 6402087      PMCID： PMC1546924          DOI： 10.1136/bmj.286.6362.333

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN： 0267-0623


  19 in total

1.  Arteriovenous anastomoses and varicose veins. Observations with the operation microscope.

Authors:  J A GIUS
Journal:  Arch Surg       Date:  1960-08

2.  Pathogenic study of varicose veins.

Authors:  P PIULACHS; F VIDAL-BARRAQUER
Journal:  Angiology       Date:  1953-02       Impact factor: 3.619

3.  Application of annihilation coincidence detection to transaxial reconstruction tomography.

Authors:  M E Phelps; E J Hoffman; N A Mullani; M M Ter-Pogossian
Journal:  J Nucl Med       Date:  1975-03       Impact factor: 10.057

4.  STUDY OF THE TENDENCY TO EDEMA FORMATION ASSOCIATED WITH INCOMPETENCE OF THE VALVES OF THE COMMUNICATING VEINS OF THE LEG. OXYGEN TENSION OF THE BLOOD CONTAINED IN VARICOSE VEINS.

Authors:  H E Holling; H K Beecher; R R Linton
Journal:  J Clin Invest       Date:  1938-09       Impact factor: 14.808

5.  The determination of regional cerebral blood flow by means of water labeled with radioactive oxygen 15.

Authors:  M M Ter-Pogossian; J O Eichling; D O Davis; M J Welch; J M Metzger
Journal:  Radiology       Date:  1969-07       Impact factor: 11.105

Review 6.  Positron emission tomography and measurements of regional tissue function in man.

Authors:  T Jones
Journal:  Br Med Bull       Date:  1980-09       Impact factor: 4.291

7.  The continuous inhalation of oxygen-15 for assessing regional oxygen extraction in the brain of man.

Authors:  T Jones; D A Chesler; M M Ter-Pogossian
Journal:  Br J Radiol       Date:  1976-04       Impact factor: 3.039

8.  ECAT: a new computerized tomographic imaging system for positron-emitting radiopharmaceuticals.

Authors:  M E Phelps; E J Hoffman; S C Huang; D E Kuhl
Journal:  J Nucl Med       Date:  1978-06       Impact factor: 10.057

9.  Transverse section imaging of soft tissue tumors and peripheral vascular disease.

Authors:  S A Gronemeyer; G L Brownell; D R Elmaleh; C A Athanasoulis
Journal:  Semin Nucl Med       Date:  1980-10       Impact factor: 4.446

10.  The use of radioactive oxygen to study muscle function in peripheral vascular disease.

Authors:  C A Clyne; T Jones; S Moss; J Ensell
Journal:  Surg Gynecol Obstet       Date:  1979-08
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  9 in total

Review 1.  Leg ulceration in venous disease.

Authors:  S K Shami; D A Shields; J H Scurr; P D Smith
Journal:  Postgrad Med J       Date:  1992-10       Impact factor: 2.401

2.  Diffusion barriers in venous ulceration.

Authors:  N F Hopkins; C W Jamieson
Journal:  J R Soc Med       Date:  1985-05       Impact factor: 5.344

3.  Causes of venous ulceration: a new hypothesis.

Authors:  P D Coleridge Smith; P Thomas; J H Scurr; J A Dormandy
Journal:  Br Med J (Clin Res Ed)       Date:  1988-06-18

4.  Venous ulceration.

Authors:  N L Browse
Journal:  Br Med J (Clin Res Ed)       Date:  1983-06-18

Review 5.  Management of leg ulcers.

Authors:  P K Sarkar; S Ballantyne
Journal:  Postgrad Med J       Date:  2000-11       Impact factor: 2.401

Review 6.  Molecular Aspects of Wound Healing and the Rise of Venous Leg Ulceration: Omics Approaches to Enhance Knowledge and Aid Diagnostic Discovery.

Authors:  Daniel A Broszczak; Elizabeth R Sydes; Daniel Wallace; Tony J Parker
Journal:  Clin Biochem Rev       Date:  2017-02

7.  Skin damage in chronic venous insufficiency: does an oxygen diffusion barrier really exist?

Authors:  T R Cheatle; G M McMullin; J Farrah; P D Smith; J H Scurr
Journal:  J R Soc Med       Date:  1990-08       Impact factor: 18.000

Review 8.  The microvascular pathophysiology of chronic venous insufficiency.

Authors:  P F McDonagh
Journal:  Yale J Biol Med       Date:  1993 Jan-Feb

Review 9.  Pathogenesis of chronic venous insufficiency and possible effects of compression and pentoxifylline.

Authors:  P D Coleridge Smith
Journal:  Yale J Biol Med       Date:  1993 Jan-Feb
  9 in total

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