Literature DB >> 6402031

Hydroperoxyeicosatetraenoic acids. Potent inhibitors of lymphocyte responses.

N Gualde, H Chable-Rabinovitch, C Motta, J Durand, J L Beneytout, M Rigaud.   

Abstract

Arachidonic acid can be transformed into a series of HPETEs by the lipoxygenase enzyme activity of mouse peritoneal macrophages. These resulting HPETEs inhibit some mouse lymphocyte responses. When mice are injected with 15-L-HPETE, their splenocytes show a decreased [3H]thymidine uptake after lectin stimulation.

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Year:  1983        PMID: 6402031     DOI: 10.1016/0005-2760(83)90181-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  5 in total

1.  Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids.

Authors:  J L Humes; E E Opas; M Galavage; D Soderman; R J Bonney
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

Review 2.  The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function.

Authors:  D J Conrad
Journal:  Clin Rev Allergy Immunol       Date:  1999 Spring-Summer       Impact factor: 8.667

3.  Stimulation of equine eosinophil migration by hydroxyacid metabolites of arachidonic acid.

Authors:  K A Potter; R W Leid; P E Kolattukudy; K E Espelie
Journal:  Am J Pathol       Date:  1985-11       Impact factor: 4.307

4.  Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation.

Authors:  R J Smith; J M Justen; E G Nidy; L M Sam; J E Bleasdale
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-01       Impact factor: 11.205

5.  Modulation of human colonic lamina propria lymphocyte proliferation. Effect of bile acids and oxidized fatty acids.

Authors:  Y Elitsur; A W Bull; G D Luk
Journal:  Dig Dis Sci       Date:  1990-02       Impact factor: 3.199

  5 in total

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