Literature DB >> 6401697

Elaboration of Bacillus anthracis antigens in a new, defined culture medium.

J D Ristroph, B E Ivins.   

Abstract

Improved culture conditions and a new, completely synthetic medium (R medium) were developed to facilitate the production of Bacillus anthracis holotoxin antigens. Levels of these antigens up to fivefold greater than the highest previously reported values were recovered with the described system. Cultures of Sterne, V770-NP1-R, and Vollum 1B strains of B. anthracis were monitored for growth, pH change, glucose utilization, supernatant protein concentration, lethal toxin activity, and protease activity.

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Year:  1983        PMID： 6401697      PMCID： PMC347970          DOI： 10.1128/iai.39.1.483-486.1983

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  19 in total

1.  An agar-diffusion method for titrating Bacillus anthracis immunizing antigen and its application to a study of antigen production.

Authors:  C B THORNE; F C BELTON
Journal:  J Gen Microbiol       Date:  1957-10

2.  Neurological and physiological responses of the primate to anthrax toxin.

Authors:  J A Vick; R E Lincoln; F Klein; B G Mahlandt; J S Walker; D C Fish
Journal:  J Infect Dis       Date:  1968-02       Impact factor: 5.226

3.  Immunologic studies of anthrax. IV. Evaluation of the immunogenicity of three components of anthrax toxin.

Authors:  B G Mahlandt; F Klein; R E Lincoln; B W Haines; W I Jones; R H Friedman
Journal:  J Immunol       Date:  1966-04       Impact factor: 5.422

4.  Biochemical and biophysical characterization of anthrax toxin.

Authors:  D C Fish; R E Lincoln
Journal:  Fed Proc       Date:  1967-09

5.  Characterization of anthrax toxin.

Authors:  M H Wilkie; M K Ward
Journal:  Fed Proc       Date:  1967-09

6.  Rapid lethal effect in rats of a third component found upon fractionating the toxin of Bacillus anthracis.

Authors:  F A BEALL; M J TAYLOR; C B THORNE
Journal:  J Bacteriol       Date:  1962-06       Impact factor: 3.490

7.  Purification and properties of in vitro-produced anthrax toxin components.

Authors:  D C Fish; B G Mahlandt; J P Dobbs; R E Lincoln
Journal:  J Bacteriol       Date:  1968-03       Impact factor: 3.490

8.  Studies on immunity in anthrax. VII. Carbohydrate metabolism of Bacillus anthracis in relation to elaboration of protective antigen.

Authors:  M PUZISS; G G WRIGHT
Journal:  J Bacteriol       Date:  1959-07       Impact factor: 3.490

9.  Comparison of growth and toxin production in two vaccine strains of Bacillus anthracis.

Authors:  A D Johnson; L Spero
Journal:  Appl Environ Microbiol       Date:  1981-06       Impact factor: 4.792

10.  DUAL NATURE OF RESISTANCE MECHANISMS AS REVEALED BY STUDIES OF ANTHRAX SEPTICEMIA.

Authors:  F KLEIN; B W HAINES; B G MAHLANDT; I A DEARMON; R E LINCOLN
Journal:  J Bacteriol       Date:  1963-05       Impact factor: 3.490
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  52 in total

1.  Autogenous regulation of the Bacillus anthracis pag operon.

Authors:  A R Hoffmaster; T M Koehler
Journal:  J Bacteriol       Date:  1999-08       Impact factor: 3.490

Review 2.  Roles of trace metals in transcriptional control of microbial secondary metabolism.

Authors:  E D Weinberg
Journal:  Biol Met       Date:  1990

3.  Transposon Tn916 mutagenesis in Bacillus anthracis.

Authors:  B E Ivins; S L Welkos; G B Knudson; D J Leblanc
Journal:  Infect Immun       Date:  1988-01       Impact factor: 3.441

4.  Glucose-dependent activation of Bacillus anthracis toxin gene expression and virulence requires the carbon catabolite protein CcpA.

Authors:  Christina Chiang; Cristina Bongiorni; Marta Perego
Journal:  J Bacteriol       Date:  2010-10-22       Impact factor: 3.490

5.  Dual promoters control expression of the Bacillus anthracis virulence factor AtxA.

Authors:  Cristina Bongiorni; Tatsuya Fukushima; Adam C Wilson; Christina Chiang; M Cecilia Mansilla; James A Hoch; Marta Perego
Journal:  J Bacteriol       Date:  2008-08-01       Impact factor: 3.490

6.  Photoreactivation of ultraviolet-irradiated, plasmid-bearing, and plasmid-free strains of Bacillus anthracis.

Authors:  G B Knudson
Journal:  Appl Environ Microbiol       Date:  1986-09       Impact factor: 4.792

7.  Role of purine biosynthesis in Bacillus anthracis pathogenesis and virulence.

Authors:  Amy Jenkins; Christopher Cote; Nancy Twenhafel; Tod Merkel; Joel Bozue; Susan Welkos
Journal:  Infect Immun       Date:  2010-11-01       Impact factor: 3.441

8.  Immunization against anthrax with aromatic compound-dependent (Aro-) mutants of Bacillus anthracis and with recombinant strains of Bacillus subtilis that produce anthrax protective antigen.

Authors:  B E Ivins; S L Welkos; G B Knudson; S F Little
Journal:  Infect Immun       Date:  1990-02       Impact factor: 3.441

9.  Identification of Bacillus anthracis by using monoclonal antibody to cell wall galactose-N-acetylglucosamine polysaccharide.

Authors:  J W Ezzell; T G Abshire; S F Little; B C Lidgerding; C Brown
Journal:  J Clin Microbiol       Date:  1990-02       Impact factor: 5.948

10.  Immunoelectrophoretic analysis, toxicity, and kinetics of in vitro production of the protective antigen and lethal factor components of Bacillus anthracis toxin.

Authors:  J W Ezzell; B E Ivins; S H Leppla
Journal:  Infect Immun       Date:  1984-09       Impact factor: 3.441
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