Literature DB >> 6400508

Studies of autoimmunity in multiple sclerosis.

J N Whitaker, D S Snyder.   

Abstract

The central nervous system myelin unit (the myelin sheath and the supporting oligodendrocyte) may be damaged by a number of immune-mediated mechanisms involving cellular or humoral factors. In this review the following areas will be considered: the composition and properties of central nervous system myelin, the chemical and biological characteristics of oligodendrocytes, the participation of the central nervous system myelin unit in experimentally induced diseases, and a description and analysis of immunological abnormalities in humans with multiple sclerosis.

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Year:  1984        PMID： 6400508

Source DB:  PubMed          Journal:  CRC Crit Rev Clin Neurobiol        ISSN： 0742-941X


  5 in total

Review 1.  Proteinases in inflammatory demyelinating disease.

Authors:  C T Bever; J N Whitaker
Journal:  Springer Semin Immunopathol       Date:  1985

2.  Enzymic methylation of myelin basic protein in myelin.

Authors:  S K Ghosh; N Rawal; S K Syed; W K Paik; S D Kim
Journal:  Biochem J       Date:  1991-04-15       Impact factor: 3.857

3.  Studies on NG-methylarginine derivatives in myelin basic protein from developing and mutant mouse brain.

Authors:  N Rawal; Y J Lee; W K Paik; S Kim
Journal:  Biochem J       Date:  1992-11-01       Impact factor: 3.857

4.  Elevated levels of a glycoprotein antigen (P-80) in gray and white matter of brain from victims of multiple sclerosis.

Authors:  T F Cruz; E J Quackenbush; M Letarte; M A Moscarello
Journal:  Neurochem Res       Date:  1986-06       Impact factor: 3.996

Review 5.  The pathogenesis of multiple sclerosis. The Bradshaw lecture 1986.

Authors:  W I McDonald
Journal:  J R Coll Physicians Lond       Date:  1987-10
  5 in total

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